All articles by Andy Extance
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Research
Visible light-powered catalysts clean up ‘forever chemicals’
Organic photoredox catalysts show promise for fluorinated pollutants
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Feature
Clearing up the compostable plastic mess
Rather than a potential triumph, the compostable plastics we use look increasingly like a tragedy. Andy Extance looks at the problems and seeks solutions
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Research
Proteins with multiple structures open up AlphaFold’s black box
AI prediction model often fails to identify fold-switching, helping show how it works and the limits of its usefulness
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Feature
How satellite remote sensing is enhancing our understanding of Earth
Instruments in space have studied the planet’s atmosphere and surface, and are now being joined by powerful new ones, finds Andy Extance
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Business
MDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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Research
AI tool outperforms existing x-ray structure methods
Deep learning approach determines phase of diffracted beams with lower-quality data
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Research
The catalyst speedup toolkit
A rundown of the various strategies scientists are exploring to cheat the Sabatier limit
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Feature
How a new strategy aims to break the catalytic speed limit
The Sabatier principle normally defines the maximum reaction rate enabled by catalyst materials, but scientists now think that they can go even faster, explains Andy Extance
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News
How can your lab cut water use in reflux reactions?
Practical advice builds on a new study comparing air-cooled condensers
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Feature
Brain chemistry basics
Andy Extance looks into the latest in Alzheimer’s disease, pain and memory
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Feature
Why don’t we know how antidepressants work yet?
Selective serotonin reuptake inhibitors are at the centre of a collision between social and biochemical outlooks on depression, finds Andy Extance
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Research
Electronic cooling device is part fridge, part muscle
Soft polymer material flexes to move heat between surfaces
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Research
Screening reveals thousands of ‘undrugged, yet druggable’ proteins
Collaboration involving Pfizer develops freely accessible AI tool to probe protein–compound interactions
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Research
First mirror-image cyclodextrins come together ‘like Lego’
L-enantiomers could be more stable than their existing, more common, forms
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Research
Carbon’s allotrope explosion demonstrates how the element is both versatile and fickle
New all carbon materials are relatively easy to predict but challenging, if not impossible to make, experts tell Andy Extance
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Research
Pulsating chemical computers vie with their quantum rivals
The Belousov-Zhabotinsky reaction powers cellular automata and optimisation calculations
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Research
Kinky findings drive crystal growth paradigm shift claim
How molecules attach chemically at surfaces can be more important than how strongly solvents bind them in determining growth rate
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Research
First GPT-4-powered AI lab assistant independently directs key organic reactions
Large language model takes control after being prompted to do Suzuki and Sonogashira couplings
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Feature
Reaching into the non-covalent toolbox
Alongside supramolecular stalwarts, budding bonding forms are vying to be valuable, finds Andy Extance
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Feature
Using DNA evidence to picture suspects
Forensic DNA phenotyping predicts people’s appearance and reveals their ancestry, finds Andy Extance, but has some significant challenges to overcome