All articles by Andy Extance – Page 3
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FeatureHow a virus ancestor powers our memory’s chemistry
Andy Extance tells the astonishing story of the Arc protein and its capsid forms, and the questions it poses
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ResearchNeural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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NewsMachine learning delivers ‘human genome’ moment for proteins
Protein structure prediction tools AlphaFold and RoseTTAFold take the latest steps towards maturity and make their software open source
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ResearchElectrochemical DNA on a chip sensor detects bacterial urinary tract infections faster
Synthetic nucleic acid probes combine with tiny star-shaped electrodes tests for bacteria in less than an hour
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NewsScientists build case for a UK x-ray laser more advanced than any in the world
Support sought for facility with higher quality, shorter pulses, to begin operation after 2030
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FeatureComputer-guided retrosynthesis
Machine learning-based systems hope to outperform expert-guided reaction planning technology, finds Andy Extance
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ResearchNitrogen deletion reaction offers ‘new way to think about molecular editing’
Reagent inspired by decades-old research could save chemists a lot of headache when it comes to modifying molecules’ skeleton
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ResearchRapidly alternating polarity stars in selective electrochemical reduction
Rapidly fluctuating AC targets specific carbonyl groups in the presence of several reducible groups
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ResearchNew definition of electronegativity fixes flaws left by Linus Pauling
Revised version of Pauling’s formula enables better predictions for problem systems such as metal-containing molecules
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ResearchTandem catalysis and smart design offer new route to polypropylene plastic
Selective combustion of hydrogen by-product improves oxidative propane dehydrogenation yields
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FeatureFlow chemistry surges forward
The long-discussed technique could help make pharma manufacturing more distributed, finds Andy Extance, and create opportunities for chemists with the right skills
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ResearchSubtle quantum phenomenon found to alter chemical reactivity for the first time
Peeking into the picosecond transition state window reveals effect of spin–orbital interactions
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ResearchCations pairs exhibit surprising attraction
‘Complex of complexes’ containing silver and iodonium ions experience an unprecendented interaction
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ResearchWalking protein’s tiny steps measured with germanium nanospheres
Highest ever resolution measurements suggests answer to kinesin dispute
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ResearchMolecular firing range allows surprisingly specific bond breaking
At energies equivalent to temperatures of several thousand Kelvin fragmentation is unexpectedly precise
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ResearchSingle atom catalysts double up to link oxidation and reduction
Photosynthesis inspires dual electrolytic system where iron-supporting shell envelops palladium-supporting ‘yolk’
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NewsLack of support undermines minority and female chemistry PhDs
US survey shows importance of peers and finances in graduate schools
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ResearchChemists tame shamanic addiction treatment
Animal experiments show modified structures remove ibogaine’s hallucinogenic and heart-harming effects
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Feature2020: the year the world changed
Andy Extance discovers how scientists around the world have responded to the pandemic, working on solutions from drugs and vaccines to hand sanitiser and PPE
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ResearchTyre compound driving mystery salmon deaths identified after years of chemical detective work
Previously unknown substance washes from roads to spawning streams – and likely has wide impact on aquatic ecosystems