Biochemistry – Page 3
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NewsmRNA vaccine pioneers win medicine Nobel prize
Katalin Karikó and Drew Weissman honoured for breakthroughs that enable the rapid development of new vaccines, including several of those used against Covid-19
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FeatureUsing DNA evidence to picture suspects
Forensic DNA phenotyping predicts people’s appearance and reveals their ancestry, finds Andy Extance, but has some significant challenges to overcome
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ResearchBiochemistry behind CBD’s anti-inflammatory effects points to new ways to treat inflammation
Cell studies unravel mechanism of action but human studies are needed
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ResearchLife’s energy currency ATP made using electricity from the grid for the first time
Simplified system uses just four enzymes with socket-supplied electrons replacing biochemical energy
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FeatureThe drug developers fighting the antibiotic resistance problem
Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments
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FeatureWho will pay for new antibiotics?
Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough
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FeatureCharting the rise in antimicrobial resistance
We look at the data behind antibiotic drug discovery and development, bacterial resistance and the financial problems with the current business model
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FeatureThe science behind a ‘runner’s high’
Exercise addicts need to stop talking about getting their endorphin hit, writes Hayley Bennett, and start looking at endocannabinoids
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ResearchMolecular fossils solve evolutionary mystery
Fossilised protosteroids confirm Nobel-prizewinner’s decades-old prediction
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ResearchAncient microbial natural products reconstructed from Neanderthal dental plaques
Palaeogenomic approach allows natural product researchers to ‘go back in time’
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FeatureA new generation of materials inspired by teeth
Ian Le Guillou finds that some of nature’s toughest structures are helping scientists to develop new fibres that could revolutionise fabrics
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ResearchOrange climbers make fluorescent blue molecules
Naturally occurring aggregation-induced emission luminogens could find use in biomedical imaging
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NewsThe launch of a new field: precision microbiome editing
Nobel laureate Jennifer Doudna is helping lead a new $70 million project combining metagenomics and CRISPR to solve health, climate problems
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ResearchNMR reveals sialic acid biosynthesis in real time
Using NMR, scientists can directly measure sialic acid enzyme conversion velocities for the first time
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ResearchWired-up symbiotic multi-organism can turn sunlight and air into valuable proteins
Symbiont could enable microfactories to produce biochemicals for food, farming and drugs
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ResearchSoapbark tree’s biosynthetic pathway for vaccine adjuvant saponins
Researchers use genome mining and bioengineering techniques to map out route
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FeatureHow do plants sense stress?
How does an organism without a brain or a nervous system sense when it’s under attack? Hayley Bennett presents the plant world’s strange yet sophisticated system for responding to wounding
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ResearchA safer, coral-friendly sunscreen is on the horizon
Polymeric UV filter doesn’t harm algae, coral or mice in tests
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FeatureChanging the game in protein structure prediction
Have AlphaFold and other machine learning techniques essentially solved the formerly fiendish problem, or is there still more to be done? Clare Sansom reports