Biochemistry – Page 8
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Research
Unnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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Feature
Metalloenzyme mastery
There are natural metalloenzymes that make difficult chemistry look easy. James Mitchell Crow talks to the bioinorganic chemists figuring out how to copy them
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Research
Unprecedented biosynthetic transformation found to connect antibacterial polyketides from ant microbiome
Study identifies enzymes that convert flat fasamycins into three-dimensional formicamycins
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Opinion
Barbara Low, penicillin and the protein pi helix
Mike Sutton celebrates the remarkable career of a female crystallographer, once mistaken for the tea-lady
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Research
First natural Diels–Alder enzyme discovered in mulberry tree
Enzyme beats most synthetic catalysts when it comes to enantioselective intermolecular [4+2] cycloadditions
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Research
Yeast thriving in hydrogen hints at possibility of life on exoplanets
First demonstration of non-adapted microorganisms growing in 100% H2 shows that life could exist even under seemingly hostile conditions
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News
Explainer: how do disinfectants tackle Covid-19?
What we know about the biocides that attack the virus, and how you should use them
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News
Science steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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Research
Engineered neurons synthesise their own conductive polymer coating
Cell-specific electric stimulation could help be used with bioelectronic prostheses or treat diseases like epilepsy
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Feature
Uncovering how the spliceosome makes the cut
Clare Sansom looks at the complex world of the spliceosome, a molecular machine in all our cells
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Research
Snakes swap toxic toads for fireflies but retain unique chemical defence
Defensive toxins reveal evolutionary shift in snakes’ diet
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Research
First Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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Podcast
Vitamin B12 or Cobalamin
If you’re trying out a vegan diet, you’re likely to be told to make sure you get enough vitamin B12. But what is B12, where do we get it from, and how can we be sure we’re getting enough?
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Feature
Can chemists crack our cells’ sugar code?
Rachel Brazil talks to the scientists trying to understand the sweet mystery of the glycome
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Research
Blood test picks out proteins that accurately predict age
Discovery could lead to better preventive medicine
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Podcast
Iminosugars
After some promising results treating ill pets, some researchers think iminosugars could become treatments for infection and even cancer. Mike Freemantle explores the buzz around iminohoney