Biology – Page 14
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FeatureChanging the game in protein structure prediction
Have AlphaFold and other machine learning techniques essentially solved the formerly fiendish problem, or is there still more to be done? Clare Sansom reports
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NewsNobel laureate and recombinant DNA pioneer Paul Berg dies
Winner of the 1980 chemistry Nobel prize has passed away in his home on Stanford’s campus at 96
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ResearchThe hunt is on for vaccine ingredients that don’t come from wild sharks
Yeast can provide the raw materials and chemical wizardry can transform them
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ResearchLipophilicity helps explain psychedelic drugs’ therapeutic effects
Understanding why psychedelic drugs that bind to serotonin receptors promote neuron growth, while serotonin itself does not
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ResearchZircon study prompts redox state rethink surrounding hydrothermal pools thought to harbour life’s first molecules
Research combining experiments with modelling suggests hydrothermal fluid was 30% as saline as sea water today and more oxidised than the surrounding mantle
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OpinionA decade on Crispr is already poised to deliver on its promise
Gene editing could transform healthcare but no disease should be forgotten
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ResearchOyster mushroom unleashes chemical warfare on its nematode prey
Fungus discovered to be using 3-octanone to paralyse and kill worms
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FeatureOmega-3s and brain health
Modern diets can leave us short on essential fatty acids. Barbara Pinho looks into how this is affecting our health and our brains in particular
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OpinionProtein filaments allow ‘diary’ of cell events to be read
Expression recording islands show when and where cells responded
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ResearchProteins behind diatoms’ intricate nanoscale-patterned shells revealed
Finding could help pattern materials for photonics, catalysis and sensors
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OpinionExploring AlphaFold’s knowledge of energy landscapes
The algorithm needs a little help to find the global energy minimum
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NewsCrispr moves into the clinic
A mere decade after its discovery Crispr is already in clinical trials for everything from sickle cell disease to HIV and cancer
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NewsEurope’s largest, hi-tech life sciences building is planned for UK
With lab space in the UK in short supply, a British property firm and Dutch real estate developer are building a massive vertical campus in London
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OpinionMass spectrometry to catch Christmas tree thieves and timber traffickers
Forensic chemistry can help uncover pine pilfering and fiendish fir felling
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BusinessTheranos leaders to be imprisoned for blood testing fraud
Sunny Balwani and Elizabeth Holmes will both serve more than 10 years
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ResearchNanoplastics disrupt ubiquitination in human cells
High-resolution study mapping nanoparticle–protein interactions builds understanding surrounding health implications of plastic contamination
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ResearchSurprise discovery as clam found to be producing complex antibiotic
Erythromycin was previously believed to be only synthesised by bacteria
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ResearchCoca plants’ production pathway for cocaine finally unravelled
167-year-old biosynthetic mystery may be solved
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OpinionElizabeth Holmes to be imprisoned for Theranos fraud
Blood testing company founder’s 11-year sentence should serve as a warning to investors
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ResearchBioelectric bacteria-powered sensor detects water contaminants in real time
Synthetic biology harnessed to detect endocrine disruptor and thiosulfate