Biology – Page 24
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ResearchComputational method challenges NMR metabolomics dogma
Macromolecule signal suppression without the loss of quantitative small molecule information finally achieved with mathematical trick
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ResearchUnnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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FeatureMetalloenzyme mastery
There are natural metalloenzymes that make difficult chemistry look easy. James Mitchell Crow talks to the bioinorganic chemists figuring out how to copy them
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ResearchUnprecedented biosynthetic transformation found to connect antibacterial polyketides from ant microbiome
Study identifies enzymes that convert flat fasamycins into three-dimensional formicamycins
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ResearchDrone blows clouds of pollen laden bubbles that could help farmers out
Automated bubble-firing drones could pollinate crops when insects numbers are down
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ResearchProteins pinpointed in cells at nanometre resolution
Combining fluorescence microscopy and electron tomography will reveal more about how cells work and how diseases disrupt them
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OpinionBarbara Low, penicillin and the protein pi helix
Mike Sutton celebrates the remarkable career of a female crystallographer, once mistaken for the tea-lady
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WebinarMedical devices: regulations and chemical characterisation
Join us for a webinar on medical device regulations and updates to extractable and leachable analysis requirements
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ResearchProtein synthesis revolution on way as large peptides made in hours not days
Flow chemistry can now make peptide chains up to 164 amino acids long in one go
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ResearchRespiratory viruses detected in 30 minutes with the help of a smartphone
$50 smartphone accessory could be adapted for Covid-19
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ResearchFirst natural Diels–Alder enzyme discovered in mulberry tree
Enzyme beats most synthetic catalysts when it comes to enantioselective intermolecular [4+2] cycloadditions
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ArticleOptimising biotech processes
Fujifilm Diosynth Biotechnologies achieve both speed and scale through designed experiments
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FeatureDrugging the gut microbiome
Treating the bacteria that live inside us can improve our own health. Clare Sansom meets our tiny friends
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ResearchDecoding the chemistry behind cicada’s bacteria-killing wings
Organisation and composition of nanostructures help to explain unique properties
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PodcastDMT – Dimethyltryptamine
Georgia Mills investigates the psychoactive found in ayahuasca that may mirror near-death experiences
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ResearchUnnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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PodcastChlorine dioxide
Katrina Krämer investigates how industrial-strength bleach became promoted as ‘miracle mineral supplement’ – a supposed ‘cure’ for autism, cancer and even Covid-19.
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ResearchPhotosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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ResearchArtificial chloroplasts turn CO2 into multicarbon molecules, powered only by light
Microfluidic platform opens up non-natural metabolic pathways
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ResearchSix-month validation behind polymer that prevents biofilm growth
Zwitterionic surface could cut infections by repelling bacteria