Biology – Page 3
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FeatureThe proteins that drive drug addiction
Jamie Durrani speaks to researchers exploring how epigenetic changes in the brain affect drug-seeking behaviours
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FeatureThe high price of a suntan
Skin cancer is on the rise in many countries around the world, but so are the methods to treat it. Bárbara Pinho reports
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ResearchGenetic engineering feat coaxes yeast to produce valuable vaccine compound
Yeast could head off supply fears for vaccines ingredient by replacing soapbark tree as source of adjuvant
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BusinessPan-cancer approval shows huge potential for antibody–drug conjugates
Enhertu gains approval based on gene expression rather than tumour location
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ResearchRodents’ striking orange teeth not down to iron-rich enamel as thought
Metal provides strength but the colour is the result of something else
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ResearchUltracold snapshots reveals in exquisite detail how a bacterial flagellum rotates
Studies explain how motor can flip from clockwise rotation to anticlockwise
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ResearchMicrobial enzymes cut a path towards universal blood for transfusions
Slicing off glycans revealed new, previously unknown antigens that must be removed to produce O-type blood
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ResearchFirst regular molecular fractal in nature
Scientists have identified a protein that has a fractal structure and find that it was simply an evolutionary accident
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ResearchScreening reveals thousands of ‘undrugged, yet druggable’ proteins
Collaboration involving Pfizer develops freely accessible AI tool to probe protein–compound interactions
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ResearchStudy raises questions about media used for in vitro tests on nanomaterials
Multiomics profiling details how biomolecular corona that form in conventional cell culture differ to those that form in human plasma
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ResearchNew mechanism identified that is potentially linked to very early stages of Alzheimer’s
Understanding role of fragments of amyloid protein could lead to novel therapies for the disease
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ResearchE. coli engineered to become methanol addict to make industry feedstocks
Bacterium could head off food versus fuel dilemma by producing chemicals from agricultural waste
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ResearchMicroscopy structures reveal mechanism behind bitter taste
Cryo-EM images provide a detailed picture of bitter taste receptors
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ResearchSelf-dyeing vegan leather made by genetically engineered bacteria
Material can be shaped into shoes and wallets, offering a sustainable alternative to traditional leather
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ResearchMicroplastics passed on during cell division
New research sheds light on the influence of microplastics on cellular processes
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BusinessUS government moves to block Chinese biotechs’ operations
WuXi Apptec and others accused of national security risk, as trade groups back legislation limiting their activities
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FeatureHow microbes influence our brain health
Our gut microbiome has been linked to conditions such as Parkinson’s and Alzheimer’s. Anthony King reports on the connections
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ResearchDeep learning algorithm predicts structures of biomolecular assemblies
RoseTTAFold extended to predict structures of proteins bound to small molecules
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ResearchStriking reptilian fossil discovered in 1931 found to be fake
280-million-year-old lizard ‘fossil’ was mostly painted on
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FeatureSmall molecules that switch up cell development could transform medicine
Turning mature somatic cells back into flexible stem cells using small molecules could revolutionise medicine, especially for regeneration and cancer. Philip Ball reports