Biology – Page 36
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FeatureCatalysts with a gentle touch
Enzymes and metal–organic frameworks share some common features and are being investigated for industrial use. Clare Sansom reports
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ResearchHole-punching antifungal used as molecular prosthesis for cystic fibrosis
Drug creates artificial ion channels that could replace broken version in cystic fibrosis patients’ lung cells
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PodcastVinblastine and vincristine: Vinca alkaloids
Kat Arney unearths a story of an overlooked female researcher in the search for the origins of cancer drugs found in plants
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ResearchStrontium isotope map re-examination casts doubt on bronze age migration theories
New findings could change the way we think about prehistoric peoples
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NewsLeading geneticists call for worldwide moratorium on creation of gene-edited children
Five-year pause would give nations breathing space following the birth of the first genetically-modified children in November
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ResearchCopper mixes with alcohol abuse drug for anticancer action
Chemical model reveals how alcoholism drug disulfiram joins copper to kill cancer cells with oxidation overload
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ResearchCracking enzyme structure offers new way to treat rare heart diseases
Solution was found by combining protein with its chaperone
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BusinessSmartwound dressings spot infection early
Bacterial toxins burst dye-filled vesicles to give a visual warning
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ResearchGenes that make lemons sour revealed
When life gives you lemons, mutate their proton pumps to make them sweeter
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ResearchThe protein crystallisation influencer
Naomi Chayen discusses her career manipulating phase diagrams to produce high-quality protein crystals
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PodcastFerrous sulfate
The iron compound that has been turning oak gall extract into indelible ink for centuries, but is now eating though our ancient manuscripts and musical scores
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ResearchGenetically engineered yeast brews up heady mix of natural and unnatural cannabinoids
Biotech yeast makes low-cost, high-quality THC and CBD – and cannabinoids never seen before – without growing cannabis plants
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Research‘Predator particles’ give mice infrared vision
Upconversion nanoparticles that bind to rods and cones shift invisible light to look green
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ResearchMineral surfaces promoted variation in prebiotic RNA
Thermodynamic model probes the entropic cost of enriching RNA strands adsorbed on a surface
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ResearchCarbon-fixing enzyme 10 times more abundant than previously thought
Calculations conclude there are 0.7 billion tonnes of rubisco in the world, an order or magnitude more than past estimates
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ResearchBuilding block approach creates new metalloproteins
Protein modules can be connected by disulfide linkages while varying the metal ions
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PodcastNitrogenase
The mysterious enzyme that can beat the world’s biggest chemical process when it comes to breaking the dinitrogen triple bond
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ResearchEight-letter genetic code hints at how alien life might evolve
Synthetic DNA shows that four bases might not be the only way for life to go
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