Biotechnology and bioengineering – Page 9
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BusinessScrambling and gambling to scale up Covid-19 medicines
Organisations work towards making billions of doses of products not yet proven to work
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ResearchUnnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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ResearchProtein synthesis revolution on way as large peptides made in hours not days
Flow chemistry can now make peptide chains up to 164 amino acids long in one go
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ArticleOptimising biotech processes
Fujifilm Diosynth Biotechnologies achieve both speed and scale through designed experiments
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FeatureDrugging the gut microbiome
Treating the bacteria that live inside us can improve our own health. Clare Sansom meets our tiny friends
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ResearchPhotosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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NewsScience steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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ResearchEnzymes encapsulated in a golden cage perform in extreme conditions
No room for the proteins to denature but reactants can still get through
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ResearchDNA instructions pack proteins into unique crystal structures
Process could aid discovery of materials that exploit specific protein functions, such as drug molecules or biocatalysts
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ResearchUniversal blood for transfusion could be created by hydrogel ‘camouflage’
Antigen-shield can prevent serious immune response to incompatible blood group
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BusinessRNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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ResearchFossilised bones inspire long-term DNA data storage
Earth alkali salts found to stabilise synthetic DNA
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ResearchDetailed 3D coronavirus spike map offers hope for vaccine development
Structure determined at ‘remarkable’ speed in little over a month
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ResearchEngineered yeast can remove heavy metals from wastewater
Easy storage and rapid growth could see yeast compete with bacterial and chemical remediation
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BusinessThe race to fight coronavirus
While genome sequences enable testing and vaccine efforts, companies are donating existing antiviral drugs to explore repurposing
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ArticleTransforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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ResearchGiant, long-lived bacteria could make microbial farms more productive
Biochemical production could be boosted using Escherichia coli engineered to grow to 13 times their usual size
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ResearchTweaking honey bee bacteria to fight colony collapse disorder
Genetically altered strains of bacteria from honey bee guts can fight virus and mites that threaten this population
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BusinessCancer and rare diseases dominated 2019 drug approvals
More streamlined review processes and changing R&D priorities have contributed to sustained increase in new medicines
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ResearchFungal enzyme given catalytic role inside lithium–air battery
Metalloenzyme changes its structure in harmony with the pH of the battery, promoting oxygen reduction and evolution as required