All blood-brain barrier articles
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OpinionMedicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge
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FeatureBypassing the blood–brain barrier
Researchers are on a quest to outsmart and overcome the sophisticated security system of the brain. Julia Robinson reports on some of the approaches being studied
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ResearchScorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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ResearchNew peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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FeatureIntracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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FeatureBreaking through the barrier
Getting drug molecules into the brain means crossing the defensive blood-brain barrier. Anthony King investigates how chemists are infiltrating the brain's fortress