Drug discovery and development – Page 10
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Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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Opinion
How the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
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Business
Why manufacturing Covid vaccines at scale is hard
Exploring the pinch points vaccine makers face as they ramp up production
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Review
The Doctor Who Fooled the World: Andrew Wakefield’s War on Vaccines
The story of the man who created the myth that a vaccine causes autism
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Business
University team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
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News
Green light for world’s first Sars-CoV-2 studies that will infect healthy volunteers
UK trials will assess how well Covid-19 treatments work and if vaccines protect against new virus variants
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Business
Coronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
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Feature
Drugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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Webinar
Physics-based computational modeling applied to the design and optimisation of biologics
Explore how FEP technology (including FEP+) can be applied in protein engineering work
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Opinion
A rough guide to pharma partnership deals
Coronavirus vaccines are driving unusual collaborations with a range of benefits
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Business
Covid vaccination efforts bolstered by trial results from J&J and Novavax
A miserable January ended with positive news on the vaccine front but new variants added complications
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Article
AstraZeneca puts academia at the heart of pharma
At the heart of chemical biology are the molecules that make medicines effective and safe for consumers. AstraZeneca harnesses the scientists at the heart of academia to create a healthier world
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News
Oxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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Opinion
Ruling out the rule of five
Simple calculations for clinical trial success failed to find a winning formula
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News
Decoding the virus – what we know about Sars-CoV-2 a year on
Scientists have never learnt so much about a pathogen in such a short time
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Webinar
High-throughput reaction screening for accelerated materials research
Learn how structure-property relationships can be used to re-design reactions or catalysts to achieve a desired activity
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Business
Can chemistry thaw the vaccine cold chain?
Covid-19 has highlighted the challenges of storing vaccines at their proper temperature. Angeli Mehta explores how scientists are trying to protect vaccines from heat degradation
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Business
Vaccine approvals offer hope as global Covid cases surge
A handful of vaccines are now approved and the first doses are being given to patients, with trials for many more candidates nearing completion
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Research
PFAS exposure found to increase risk of severe Covid-19
Warnings that high levels of per- or poly-fluorinated substances might also reduce the effectiveness of a vaccine
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Business
Pharmaceuticals roundup 2020
Alongside the race for Covid-19 treatments and vaccines, the industry has maintained momentum