Drug discovery and development – Page 11
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WebinarFaster drug discovery and optimisation with physics-based computational methods
Learn how physics-based computational methods, such as Free Energy Pertubation (FEP) calculations, can speed up the drug discovery and lead optimisation
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ResearchChemists tame shamanic addiction treatment
Animal experiments show modified structures remove ibogaine’s hallucinogenic and heart-harming effects
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BusinessCybercriminals target Covid-19 vaccines
Officials in the UK and US warn of threat from cyber-attacks that steal data related to Covid-19 vaccines and aim to disrupt the supply chain
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Feature2020: the year the world changed
Andy Extance discovers how scientists around the world have responded to the pandemic, working on solutions from drugs and vaccines to hand sanitiser and PPE
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BusinessPfizer–BioNTech vaccine gains emergency approvals in US, Canada and beyond
UK begins vaccinating vulnerable populations after early authorisation
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ResearchAnimal tests reveal synthetic decoy protein protects against coronavirus
Protein designed from scratch binds Sars-CoV-2 with high affinity and specificity
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BusinessUK grants Pfizer–BioNTech Covid-19 vaccine emergency approval
Regulators around the world working towards accelerated decisions on vaccine data
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BusinessOxford–AstraZeneca vaccine joins others with promising interim data
Cheap and fridge-stable candidate at least 60% and up to 90% effective at preventing disease
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BusinessRegulatory panel unconvinced by Alzheimer’s antibody evidence
US FDA advisors vote against approving Biogen’s aducanumab on the basis of incomplete data analysis
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WebinarEmerging strategies in covalent inhibition
Join us for a review of emerging strategies for the development of covalent inhibitors in drug discovery
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BusinessModerna and Pfizer’s Covid-19 vaccines add more encouraging data
Pfizer–BioNTech reach safety threshold for emergency authorisation, while Moderna’s data peek suggests 95% efficacy
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NewsTen chemistry innovations that Iupac says could change the world
How chemistry can tackle plastic recycling, climate change and Covid-19 among other challenges
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ArticleFaster pharma: Catalytic innovation combats precious metals supply chain pain
Precious metal catalysts are key to pharma but subject to market forces that make reliance on supply a double-edged sword.
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ReviewBiography of Resistance: The Epic Battle Between People and Pathogens
A book illustrating a global health threat more daunting than Covid-19: growing antibiotic resistance
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OpinionThe ins and outs of vaccine trials
Derek Lowe lays out how the trials work, and why they get paused and restarted
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OpinionA promising peep at Covid-19 vaccine efficacy
Pfizer–BioNTech’s will need to be one of many if we are to overcome the pandemic
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BusinessEarly indications suggest Pfizer–BioNTech’s Covid-19 vaccine is effective
Company claims 90% efficacy at preventing disease, but experts call for data rather than press releases
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ResearchNanoparticle can starve aggressive breast cancer cells of vital copper
A new engineered particle depletes copper from mitochondria, killing breast cancer cells in mice
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OpinionEthical challenge
Should researchers infect healthy people with Sars-CoV-2 to speed up vaccine testing?