Drug discovery and development – Page 18
-
-
FeatureMalaria no more?
Efforts to cure malaria have been going on for hundreds of years. Clare Sansom looks at some of the latest – and most innovative
-
NewsPilot malaria vaccination programme begins in Malawi
Mosquirix vaccine will be rolled out in Ghana and Kenya next week
-
-
ResearchSynthetic enzyme wipes out tough bacterial biofilms
After success in mice strategy could be an alternative to antibiotics to treat wounds
-
ResearchDroplet screening set to accelerate immunotherapies into the clinic
Single-cell technique eliminates inefficiencies when identifying immune cells active against specific cancers
-
ResearchCo-crystals fish out cannabinoid from plant extract
Purifying cannabidiol from natural cannabis extract made cheap and easy thanks to amino acid partner
-
ResearchNew family of peptides from extremophile show antibiotic promise
Scientists isolate salinipeptins from a bacterium living in America’s Dead Sea
-
ArticleSmall particles making a big splash in clinical development
Nanoform is investigating how to tackle clinical attrition rates through nanonisation of APIs
-
ArticleInvestigating multi-dimensional problems in drug substance development
Finding solutions to the biggest challenges faced during drug substance development relies on properly integrating analytical and production expertise
-
ResearchSmall molecule finds flu virus’s weak spot
Drug candidate that targets highly conserved region of virus gave mice complete protection from swine flu
-
FeatureThe battle to lose weight
Losing weight – and not putting it back on – is about much more than willpower. Nina Notman reports on the drugs trying to penetrate the complex metabolic web of hunger and satiety.
-
ResearchCracking enzyme structure offers new way to treat rare heart diseases
Solution was found by combining protein with its chaperone
-
ResearchGenetically engineered yeast brews up heady mix of natural and unnatural cannabinoids
Biotech yeast makes low-cost, high-quality THC and CBD – and cannabinoids never seen before – without growing cannabis plants
-
ResearchThe five reactions on every organic chemist’s wish list
Synthesis has some catching-up to do to create the reactions every drug discovery chemist dreams of
-
-
FeaturePass the antidote
From paracetamol to pesticides – not to mention nerve agents – there are many toxic compounds that doctors need to be able to counteract. Nina Notman investigates
-
NewsPersonalised medicine has failed to live up to the hype, researchers claim
Predictions that Human Genome Project would usher in an era of tailored therapies have largely failed to come true
-
OpinionHow teenagers are disrupting drug discovery
A citizen science project to improve access to malaria drugs
-
BusinessUK government sets out antimicrobial resistance plan
Aims to cut antibiotic use and explore financial incentives for pharmaceutical companies