Drug discovery and development – Page 26
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NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
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ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
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ResearchGold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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PodcastThiomersal
Kat Arney introduces the organomercury preservative associated with the current controversy around vaccines
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OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
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OpinionLinked data is the future for medicinal chemistry
Paul Groth explains why linked data is starting to revolutionise medicinal chemistry
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ResearchMirror-image trick yields real hits from a virtual chemical library
Scientists use mirror-image protein to identify potential new drugs from a previously unexplored library of natural product enantiomers
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Feature2Heavy drugs gaining momentum
With the first approval of a drug containing deuterium looking imminent, Nina Notman surveys the deuterated drug landscape
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NewsWorld faces tough challenge turning words into action on antibiotic resistance
Countries are waking up to the challenge of ‘superbugs’ but agreeing a way forward will be tricky
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ResearchChemical synthesis injects new life into old antibiotics
Approach can construct wide range of new antibiotic candidates from simple chemical building blocks
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News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November
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BusinessFDA moves to withdraw swine drug carbadox
Carcinogenic antibiotic has been banned in EU, Canada and Australia for years
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OpinionDrugs don’t grow on trees
The trope of companies profiteering from academic discoveries doesn’t bear much scrutiny, says Derek Lowe
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BusinessSanofi and Merck & Co end vaccines partnership
Two-decade-long alliance will split by end of 2016
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NewsThe huge impact of ‘mini-brains’
‘Mini-brains’ created by Johns Hopkins researchers in the US could revolutionise how drugs and compounds are tested for safety and effectiveness
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News‘Map’ of chemical landscape could cut animal testing
Searchable database of 10,000 chemicals could help to create safety profiles for untested compounds
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PodcastFlibanserin
Flibanserin was touted to be the female Viagra. Martha Henriques explains why it failed to live up to the hype.
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NewsAntibiotic alternatives need to be recruited in fight against resistance
Vaccines, probiotics and other substitutes could help battle antimicrobial resistance as antibiotic effectiveness fades
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FeatureAge of the phage
Hayley Birch discovers how researchers are using proteins from viruses to create new antimicrobial drugs