Drug discovery and development – Page 27
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ResearchBoost for non-animal toxicology testing
Thousands of compounds have been screened in a bid to develop in vitro toxicity tests
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OpinionThe kids aren’t alright
Making it more attractive for companies to develop paediatric drugs has the potential to improve everyone’s lives
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BusinessClinical trial death highlights hazards
Pain drug trial has left one dead and five hospitalised in France, with little indication as to the cause of the problems
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ResearchDrug labelling problems ironed out by new catalyst
Cost-effective method to tritiate compounds offers way to track drug metabolism while minimising radioactive waste
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ResearchEasy addition of ‘unnatural’ strained rings boon for drug chemists
Technique can slow metabolism of medicines, giving them more time to work
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BusinessFixing the broken antibiotics business model
With rising resistance and doomsday warnings, focus is turning to alternative economic models to boost antibiotic R&D
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Business
Mexico approves world’s first dengue vaccine
Sanofi’s vaccine protects children and adults against the mosquito-borne disease
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Business
BioAtla and Pfizer to collaborate on antibody research
Two-way agreement to share technology and royalties on new cancer drugs
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Business
Heptares takes on new partners for drug discovery
Firm set to receive over $1bn from research partnerships
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NewsReview calls for tighter controls on antibiotic use in farming
Legally binding targets are needed to tackle resistance worldwide, latest report says
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Business
Drug firms to share chemical compound libraries
AstraZeneca and Sanofi aim to facilitate drug discovery by swapping 210,000 proprietary chemical compounds
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NewsPoor management of antibiotics squandering life-saving drugs
Internet and over-the-counter sales along with counterfeit drugs are driving a worldwide rise in antimicrobial resistance
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FeatureMolecule-making microbes
Extracting terpene drugs from plants is difficult and wasteful, so pharma companies are looking to biosynthesis, as Emiliano Feresin discovers
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BusinessViral cancer therapy approved in the US
T-Vec is the first approved oncolytic virus, but its limited treatment scope means it is unlikely to become a blockbuster
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ResearchEye drops show promise treating cataracts and even reversing damage
Sterol compound can ‘dissolve’ mis-folded proteins to help clear the lens offering hope to 100 million in developing world
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NewsPoor diagnostics hinder battle against antibiotic resistance
Healthcare workers’ tools to diagnose infections remain stuck in the past