Drug discovery and development – Page 34
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Opinion
New antibiotics: what's the hold up?
It’s more a research problem, than a commercial one, says Derek Lowe
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NewsPharmaSea to scour ocean depths for new drugs
Bioprospecting project will investigate marine organisms in the search for new antibiotics and central nervous system therapies
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Business
Flu vaccine without the eggs approved
Flublok does not require flu virus or eggs for manufacture
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Business
TB drug milestone for bedaquiline
First TB drug with a new mechanism of action for 40 years wins approval
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FeatureMaking pain history
From ancient folk remedy to the wonder drug of the early industrial age and beyond. Mike Sutton traces the remarkable history of aspirin
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Business
Return on drug R&D dropping
The pharma industry is getting less and less return on investment in R&D but trend seems to be bottoming out
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Business
Drug R&D costs rising
Review from UK consultancy suggests ten-fold increase in per medicine R&D costs over last 30 years
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CareersNobel signals for new drugs
Sarah Houlton talks to a company that’s capitalising on the chemistry of communication
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Business
Bayer and Evotec team up on endometriosis
German collaboration aims to develop three drug candidates in five years
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NewsChinese drug makers accused of using ‘gutter oil’
Oil reclaimed from drains may have been used to make an antibiotic intermediate
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FeatureFood with a function
Compounds normally thought of as medicines are being added to food. Elinor Hughes looks at the scientific and regulatory challenges facing these nutraceuticals.
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OpinionMonopoly money
Dean Baker says it’s time to start talking seriously about the way in which pharma is funded
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OpinionProtecting patients at all costs
Suffering stagnant output, and beset by patent expiries and spiralling costs, drug discovery is in poor health. Simon Campbell prescribes a remedy
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FeatureFast, flexible and flourishing
Paul Workman’s experiences in big pharma, academia and biotech gave him the tools to develop new drugs and spin out successful companies. Sarah Houlton profiles the 2012 Chemistry World entrepreneur of the year
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FeatureDrawing on drugs to kick the habit
While pharma companies stand accused of giving up on drugs to help people stop smoking, tobacco firms are looking at controversial nicotine replacement products. Anthony King surveys an area that is problematic on all sides.
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OpinionPeace, love and understanding
Chemists and biologists often view the process of drug discovery very differently
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News€224 million EU antibiotics initiative launched
The project will bring together the pharmaceutical industry and academia, but some institutes have reservations
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BusinessHDL drug class struggling after latest flop
The failure of another ‘good’ cholesterol-raising drug and a new genetic study casts shadow over HDL hypothesis
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NewsVoluntary controls on antibiotics on US farms criticised
The US Food and Drug Administration has introduced guidelines to try to cut antibiotic use in livestock