Drug discovery and development – Page 5
-
BusinessEncoding creativity in drug discovery
Machine learning can complement and reinforce human intuition and experience
-
OpinionA decade on Crispr is already poised to deliver on its promise
Gene editing could transform healthcare but no disease should be forgotten
-
![Chemical structure of Pillar[6]MaxQ](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/6/2/1/523621_chempr1747_proof1_891632.jpg)
ResearchMolecular trap that snares many different drugs could save lives during overdoses
Macrocyclic compound can mop up drugs of abuse in animal tests – including those for which no reversal agent exists
-
OpinionSetting drug development speed records
The pandemic treatment sprint was spectacular, but hard to match under less unusual circumstances
-
ResearchBenchtop machine automates synthesis of drug screening hits
System could boost the efficiencies of drug discovery campaigns
-
BusinessUK antibiotics supply chain stretched by surge in Strep A infections
Government enacts protocols to enable substitute treatments and recommends preventive prescriptions in severe cases
-
NewsCrispr moves into the clinic
A mere decade after its discovery Crispr is already in clinical trials for everything from sickle cell disease to HIV and cancer
-
BusinessPharmaceuticals roundup 2022
Following the huge success of vaccines and treatments for covid-19, companies are upping their investment in R&D and dealmaking
-
ResearchUniversal flu vaccine could head off future pandemics
More effective mRNA-based vaccine offers hope of ending annual flu shots for at risk groups
-
ResearchSurprise discovery as clam found to be producing complex antibiotic
Erythromycin was previously believed to be only synthesised by bacteria
-
ResearchRadium chelator researchers working to improve targeted cancer therapies
Oak Ridge National Lab team investigate factors underpinnning Ra2+ complex stability and selectivity in attempt to expand the therapeutic utility of radium-223
-
OpinionEmbracing oddities
When new chemistry looks like alchemy or witchcraft, it’s worth taking notice
-
NewsWorld Health Organization takes aim at market as many still not getting vaccines they need
Government, industry and health organisations must do more
-
ResearchDiverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds
-
-
-
ResearchAmide library created at speed with machine learning and stopped-flow chemistry
Approach used 90% less starting material than continuous flow equivalent
-
FeatureTiny delivery systems for cancer drugs
Encapsulating anticancer agents in nanoparticles can make them gentler on the rest of the body. Clare Sansom reports
-
OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
-
BusinessAlzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers