Drug formulation and delivery – Page 5
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ResearchScorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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PodcastFuranocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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ResearchFirst oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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NewsNew life sciences institute wants to make drug discovery 10 times more efficient
The UK’s £103 million Rosalind Franklin Institute will unite robotics, chemistry and biophysics to generate drug candidates within weeks
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ArticleAre polymer medicines viable therapeutics?
Combining small-molecule medicines with polymers could offer big rewards for pharmaceutical researchers
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Feature3D printing in pharma
Nina Notman explores how 3D printing is carving out a niche for itself in the pharmaceutical industry
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OpinionWhy combination pills aren’t always the answer
The challenges of medicines containing multiple drugs aren’t going away
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BusinessFit for repurpose
Drugs that can be used for new indications offer a potentially cheaper pathway – but only if the investors can recoup their costs
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ArticleIs industry ready for the serialisation shake-up?
The regulation few outside of pharma have heard about
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ArticleDriving pharmaceutical innovation
Making drugs is neither easy nor cheap – but catalysts, flow chemistry and a knowledge of intermolecular interactions can help
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ArticleDissolving insoluble drugs
How spray drying can help with solubility and bioavailability challenges in drug development
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FeatureThe chemistry of the microbiome
Our gut bacteria are carrying out chemistry on our behalf, but without us knowing much about it. Now, scientists are starting to examine their enzymes
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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FeatureArtificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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BusinessDrug formula change infuriates French thyroid patients
Poor communication of changes to Merck KGaA’s levothyroxine has led to complaints of side effects
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ResearchResponsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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FeatureDelivering gene therapy
After some well-publicised problems, gene therapy – delivering DNA into people’s cells using viruses – is booming, Anthony King finds
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ResearchBlue nanoparticles mop up radioactive element
Nanosized Prussian blue formulation removes radioactive caesium from body faster than commercial treatment
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FeatureIntracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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FeaturePersonalised skincare
Nina Notman explores some of the latest scientific approaches skincare companies are using in the quest to develop high-earning anti-ageing cosmetics