Drug formulation and delivery – Page 6
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ResearchMicroscopic cannon battery to blast disease
Cannon-like tubes shoot tiny bullets when triggered by ultrasound and could deliver drugs
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ResearchOral delivery of anticancer drug
Researchers endeavour to limit drug side effects and injections for cancer patients
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ResearchCobalt could cut costs for pharma ingredients
Carboxylic acids and esters hydrogenated without the need for expensive precious metals
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FeatureA new hope in HIV prevention
New microbicide products could turn the tide against Aids for women in Africa, reports Dinsa Sachan
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FeatureOligonucleotide drugs step up
Structural innovations are overcoming oligonucleotide drugs’ historical flaws, discovers Andy Extance
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BusinessPorous pills could be largest industrial 3D printing use
US grants first-of-a-kind approval for Aprecia’s epilepsy tablets exploiting porous structure
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ResearchSingle polymer pill could deliver entire drug course in one go
Flexible elastomer ring springs open to stay in stomach and could slowly release drugs over days
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OpinionMissing the target
There are plenty of things that small molecule drugs can’t touch, says Derek Lowe, and it’s not for want of trying
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ResearchRegulators have drug firms chasing phantom impurity
Mutagenic contaminants that supposedly form in sulfonic acid salts are highly unlikely to arise
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ResearchDNA inspires smart phospholipids
Liposomes made from synthetic nucleoside phospholipids could benefit drug delivery
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FeatureImaging the future
Doctors and pharmaceutical companies are beginning to open their eyes to the power of mass spectrometry imaging, finds Nina Notman
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ResearchHydrogel with a basic instinct for drug delivery
Gel that releases naproxen in alkaline surroundings is promising step toward relieving drug’s side effects
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ResearchSpicing up MOFs
Framework based on the turmeric pigment curcumin delivers two drugs for the price of one
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ResearchTea tonic peps up tumour treatment
Green tea polyphenol makes ‘magic bullet’ cancer drug delivery even more powerful
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ResearchMirror peptides hitch a lift into the cell
Hijacking nature’s tricks to smuggle drugs across the cell membrane
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ResearchNanoparticle protects protein drug cargo
Proteins cling to co-polymer thanks to electrostatic interactions
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FeatureSeek and destroy
Nanoparticles that can find specific targets before delivering a drug could change medicine. Akshat Rathi investigates
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FeatureFrom molecules to medicines
Turning an active drug molecule into a finished product requires as much chemistry as developing the drug in the first place, as Phillip Broadwith discovers