All enantioselectivity articles
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ResearchEnantioselective synthesis of elusive chiral nitrogen compounds discovered by chance
An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition
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ResearchAI enantioselectivity predictor set to power computational catalyst screening
Workflow involves mapping a reaction representation onto the activation energy of the stereocontrolling step
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ResearchCatalyst takes its time to deliver both enantiomers in one pot synthesis
Discovery could enable access to both enantiomers of a drug in a single synthesis
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ResearchCounterintuitive catalyst gives purer products when used in less enantiopure form
Unusual example of ‘hyperpositive’ nonlinear effect is a first for asymmetric catalysis
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ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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ResearchMagnets on hand for separating chiral crystals
Enantiomers crystallise individually at opposite magnetic poles, driven by interactions with electron spin
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ResearchFlexible catalyst systems open up nitrile chemistry
One new strategy enantioselectively produces amines from nitriles, and another generates valuable alkenyl nitriles
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ResearchCoulomb explosion uncovers laser-driven chirality
Blowing formic acid apart like a firework sheds light on asymmetric photochemical synthesis
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OpinionChiral curiosities
The challenges posed by asymmetry go hand in hand with fascinating insights into developmental biology
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ResearchLight catalyst breaks mirror symmetry in first reverse racemisation
Transformation makes single mirror image molecules in a ‘completely different way of doing enantioselective chemistry’
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Research2D membrane sieves out amino acid enantiomers
Molecular sheets can separate racemic mixtures with high efficiency and selectivity
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ResearchEnzyme helps photoredox get enantioselective
Enantioenriched amine synthesis is inaugural example of photoredox and enzyme collaboration
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ResearchMagnetism puts new spin on separating mirror image molecules
Enantiomers can be identified and separated using a magnetised substrate
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ResearchChallenging mirror molecules made with stereochemistry destroying reaction
Clever catalyst repurposes classic nucleophilic substitution to make chiral quaternary carbon centres
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ResearchChiral catalyst switches selectivity in seconds
Helical copper compound’s enantioselectivity can be inverted while reaction is running
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ResearchTemperature drop triggers chirality twist
Asymmetric reaction’s enantioselectivity turned on its head