Well plate

Mapping metabolite disturbances by drugs

High-throughput metabolomic profiling gives insight into unpredictable drug effects

Chemistry practical

Chemical sciences workforce growth could outstrip rest of UK over next 10 years

Royal Society of Chemistry report says support for schools, universities and industry is needed for sector to thrive

Purdue settlement deal

New Purdue bankruptcy deal cuts out Sacklers’ legal immunity

$7.4 billion proposal will fund support for victims of US opioid crisis

Telescope

Maintaining mental balance

Finding solace from human affairs in the eypiece of a telescope or microscope

Highlights

Paper shredder shredding a protein structure

The promise of drugs that send proteins to the shredder

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to strategic discovery

Gas flaring

Chemicals industry roundup 2024

Europe continues to struggle with high energy and feedstock costs, while US and Asia negotiate supply gluts

Ozempic and Wegovy

Pharmaceuticals roundup 2024

Diabetes and weight loss drugs have surged in popularity, revealing supply frailties

Serbia protest

Opposition to lithium mines hampers green technology supply chain

Europe and US seek to escape Chinese dominance in critical minerals

Bhopal disaster

Forty years on from the Bhopal disaster what lessons have been learnt?

India looks to the future as survivors fight on to receive adequate compensation and medical care

Purdue settlement deal

New Purdue bankruptcy deal cuts out Sacklers’ legal immunity

$7.4 billion proposal will fund support for victims of US opioid crisis

Two miniature figures in suits standing on jigsaw pieces

J&J’s Intra-Cellular deal could signal more mega-mergers for 2025

£15 billion deal for neuroscience biotech aims to replace revenues from patent expiries

Queue of robots

Robots queuing up to fail

Claims of an AI revolution in drug discovery are missing the biggest problem

Leen Kawas

Athira pharma settles research misconduct charges for $4 million

Deal with US Department of Justice resolves allegations against former chief executive

Purdue settlement deal

New Purdue bankruptcy deal cuts out Sacklers’ legal immunity

$7.4 billion proposal will fund support for victims of US opioid crisis

Eight workers dead in Indian munitions factory explosion

Seven others injured during incident at state-owned explosives plant

J&J’s Intra-Cellular deal could signal more mega-mergers for 2025

£15 billion deal for neuroscience biotech aims to replace revenues from patent expiries

Red 3 dye banned in US food and drugs

Additive was already banned in US cosmetics and around the world

Sharing the burden of contraception could also mean sharing the risk

What if risk assessments for contraception considered the sum of risk to both members of a couple?

Athira pharma settles research misconduct charges for $4 million

Deal with US Department of Justice resolves allegations against former chief executive

Well plate

Mapping metabolite disturbances by drugs

High-throughput metabolomic profiling gives insight into unpredictable drug effects

Structure

Metal–organic framework captures carbon dioxide at industrially relevant temperatures

Material could improve energy efficiency of capturing carbon from industy’s exhaust gases

Fluorite

Fluorspar to fluorine chemicals without going via hazardous hydrogen fluoride

Safer way to turn calcium fluoride mineral into valuable industrial materials

Banned pigments found in tattoo inks sold in the EU

Nine out of 10 green and blue inks analysed violate Reach regulations

Nanopore sequencing set to transform our understanding of proteins

Rapid sequencing technique can not only deal with proteins hundreds of amino acids long but can detect modifications

How F1 plans to transition to ‘100% sustainable fuel’

Rule changes intend to make Formula One more environmentally friendly from 2026. But what are the changes, and can a sport known for gas-guzzling engines really go green?

PFAS-free synthesis of fluorinated drugs and pesticides

Flow chemistry introduces trifluoromethyl group onto a range of compounds using just caesium fluoride as the fluorine source

Potential new class of antibiotics takes on flesh-eating infections

Peptide-mimicking compounds target bacterial cell walls

Explosion

Eight workers dead in Indian munitions factory explosion

Seven others injured during incident at state-owned explosives plant

Red 3 dye banned in US food and drugs

Additive was already banned in US cosmetics and around the world

US state charges Lockhart director over river chemical release

Bankrupt firm’s leader accused of endangering the public and altering public records

PFAS manufacturers sued for deceptive marketing in US

Texas attorney general accuses 3M and DuPont of knowingly concealing health risks

Chemicals industry roundup 2024

Europe continues to struggle with high energy and feedstock costs, while US and Asia negotiate supply gluts

Deadly explosion at US food colouring plant

2 workers dead, 11 injured at Givaudan Sense Colour in Louisville

Two miniature figures in suits standing on jigsaw pieces

J&J’s Intra-Cellular deal could signal more mega-mergers for 2025

£15 billion deal for neuroscience biotech aims to replace revenues from patent expiries

Doliprane Paracetamol

Sanofi spins out its consumer healthcare business

US-based investment firm takes controlling stake in Opella, while France’s government moves to ensure the company remains in the country

Covestro

Adnoc to buy Covestro, continuing expansion into polymers

€15 billion deal sees Gulf oil producer looking to future growth beyond fuels