All articles by Karl Collins
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Opinion
Fully automated synthesis of fluorine-18 PET tracers
Making radioisotopes suitable for positron emission tomography
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Opinion
Taking benzyl fluorides beyond game changing reports
Decarboxylative cross-coupling to produce benzyl fluorides
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Opinion
Exploring nickel reactivity in C–H activation chemistry
Coming closer to an alternative for palladium
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Opinion
Stereoselectivity with a twist
Helical ligands amplify solvent chirality to control reaction outcomes
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Opinion
‘Coffee machine’ synthesiser’s first steps
Cartridge-based machine enables non-experts to make heterocycles
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Opinion
In search of ultimate selectivity
A catalyst that reacts only with aryl iodides, spurning bromides and chlorides
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Opinion
Combining Lewis acid and redox catalysis
Organic phenalenyl cations perform a dual role without transition metals
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Opinion
Making light work of synthesis
The LED zeppelin is flying high, but is it all hot air asks Karl Collins
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Opinion
Ketones perform at the palladium
C–H activation takes the stress out of organometallic couplings
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Opinion
Forcing fluorines into shape
Sometimes unnatural molecules can be more challenging to synthesise than natural metabolites
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Opinion
Nickel catalyst couples alcohols and carbon dioxide
Flexibility and low cost make nickel a firm favourite in catalysis
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Opinion
Functionalising pyridines with phosphonium salts
Newly-independent research groups often bring new perspectives to synthesis
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Opinion
Lighting up crowded corners
Combining photocatalysis with organocatalysis opens doors to chiral quaternary centres
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Opinion
An odd couple
Coupling unactivated phenols with amines requires an unusual approach, as Karl Collins discovers
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Opinion
Scratching chiral surfaces
Heterogeneous asymmetric catalysis beyond hydrogenation is tricky, says Karl Collins
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Opinion
A witches’ brew for trifluoromethylation
Karl Collins is surprised by the difficulty of a seemingly simple alkylation
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Opinion
Dispelling nickel’s catalytic demons
Stable Ni(IV) complexes could help nickel rival its flashier platinum-group cousins, says Karl Collins