All Life articles – Page 14
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ResearchAntigen-carrying adjuvants activate both adaptive and innate immunity
Aluminosilicate nanoparticles promote ion perturbation, pyroptosis and enhanced immunity in a cancer model
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BusinessHaleon emerges from GSK consumer healthcare spin-off
Split illustrates move towards narrower focus in pharmaceuticals
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FeatureHow a murder and a bombing cleaned up DNA profiling
The UK pioneered a forensic process to identify suspects from tiny amounts of DNA, but occasional flaws had big consequences. Andy Extance pieces together the whole story for the first time
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ResearchTheories on origin of enzymes’ catalytic power united
Transition state stabilisation and ground state destabilisation both reduce the energy barrier by enhancing charge density but vary in their timing
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ResearchMystery of how plants make strychnine solved 75 years after characterisation
Three-quarters of a century after Robinson and Woodward cracked structure chemists unravel poison’s biosynthesis
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BusinessCalifornia advances plans to make its own insulin
Governor commits $100 million to develop low-cost insulin and build manufacturing facility to strengthen drug’s supply chain
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BusinessSecond Theranos executive convicted of fraud
Blood testing startup president Ramesh ‘Sunny’ Balwani defrauded both investors and patients
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ResearchRenewable rocket fuel made by genetically engineered soil bacteria
Bioengineered bacteria synthesise extremely energy dense cyclopropane chains
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OpinionAlzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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ResearchThe odour of amity: how you smell can predict friendships
Strangers who smell alike tend to form an instant connection with each other on first meeting
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NewsNew questions raised over Sputnik Covid vaccine results point to fraudulent practices
Analysis comparing Sputnik results with five other Covid vaccines finds phase 3 trial outcome is highly improbable
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ResearchEncapsulated bacteria show promise as injectable living drugs factories to treat diseases
Engineered E. coli produce insulin and vaccines in vivo
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OpinionFrom prebiotic soup to fine-grained RNA world
Theories about how life emerged need to be closely attuned to conditions on the early Earth
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FeatureUsing genetics to personalise prescriptions
We’ve known for a long time that different people respond to certain drugs to very different extents, but now cheap DNA testing could make these disparities a thing of the past, as Ian Le Guillou reports
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ResearchLight-activated cancer treatment uses tumour-targeting enzymes to cut side effects
Enzymatic activation of a photosensitive prodrug in cancerous cells shows promise in mice
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NewsQuestion marks over cannabidiol’s safety in food, European agency finds
Food safety body has already received more than 150 applications to add CBD to food products
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ResearchFossil molecules reveal dinosaurs’ bird-like metabolism
Thioethers preserved in bones show that most dinosaurs were warm-blooded, though T rex may have been particularly sluggish
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BusinessData reveals disparities in US refinery benzene emissions
Monitoring shows several facilities consistently exceed federal action levels
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