All Life articles – Page 44
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Article
Investigating multi-dimensional problems in drug substance development
Finding solutions to the biggest challenges faced during drug substance development relies on properly integrating analytical and production expertise
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Research
Hole-punching antifungal used as molecular prosthesis for cystic fibrosis
Drug creates artificial ion channels that could replace broken version in cystic fibrosis patients’ lung cells
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Research
Strontium isotope map re-examination casts doubt on bronze age migration theories
New findings could change the way we think about prehistoric peoples
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News
Leading geneticists call for worldwide moratorium on creation of gene-edited children
Five-year pause would give nations breathing space following the birth of the first genetically-modified children in November
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Research
Copper mixes with alcohol abuse drug for anticancer action
Chemical model reveals how alcoholism drug disulfiram joins copper to kill cancer cells with oxidation overload
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News
Adding CBD to everything from soft drinks to cakes prompt warnings
US authorities start to take action on cannabidiol additives
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Research
Small molecule finds flu virus’s weak spot
Drug candidate that targets highly conserved region of virus gave mice complete protection from swine flu
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Feature
The battle to lose weight
Losing weight – and not putting it back on – is about much more than willpower. Nina Notman reports on the drugs trying to penetrate the complex metabolic web of hunger and satiety.
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Research
Cracking enzyme structure offers new way to treat rare heart diseases
Solution was found by combining protein with its chaperone
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Business
Smartwound dressings spot infection early
Bacterial toxins burst dye-filled vesicles to give a visual warning
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News
University sues professor for taking graduate’s research that he stands to make millions from
University of Missouri–Kansas City pharmacy researcher accused of stealing inventions related to a novel eye drug delivery formulation, sold it for $1.5m plus royalties
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Research
Genes that make lemons sour revealed
When life gives you lemons, mutate their proton pumps to make them sweeter
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Research
The protein crystallisation influencer
Naomi Chayen discusses her career manipulating phase diagrams to produce high-quality protein crystals
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Podcast
Humble Pi: A Comedy of Maths Errors by Matt Parker – Book club
Matt Parker uses comedy to explore the unique relationship between humans and maths and how numbers are behind errors large and small
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News
Genome sequencing for healthy dismissed as waste of time for UK project
Personalised medicine plan unlikely to deliver any benefits for the wider population
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Research
Genetically engineered yeast brews up heady mix of natural and unnatural cannabinoids
Biotech yeast makes low-cost, high-quality THC and CBD – and cannabinoids never seen before – without growing cannabis plants
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Research
‘Predator particles’ give mice infrared vision
Upconversion nanoparticles that bind to rods and cones shift invisible light to look green
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Research
Mineral surfaces promoted variation in prebiotic RNA
Thermodynamic model probes the entropic cost of enriching RNA strands adsorbed on a surface
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Research
Carbon-fixing enzyme 10 times more abundant than previously thought
Calculations conclude there are 0.7 billion tonnes of rubisco in the world, an order or magnitude more than past estimates
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Research
Building block approach creates new metalloproteins
Protein modules can be connected by disulfide linkages while varying the metal ions