Medicinal chemistry – Page 16
-
Research
Machine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
-
Article
Digital technologies in the personalised medicines revolution
The revolution will be digitalised
-
Article
Unlocking the future of medicines manufacturing with digital innovations
The Medicines Manufacturing Innovation Centre promises to revolutionise how we formulate, trial and produce medicines
-
Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
-
Opinion
How the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
-
Business
Why manufacturing Covid vaccines at scale is hard
Exploring the pinch points vaccine makers face as they ramp up production
-
Research
Molecular pendulum sensors could track and monitor disease
DNA–antibody probes can detect specific proteins inside a live subject
-
Opinion
Why are impurity regulations different for food and drugs?
The pharmaceutical and food industries should work together more closely on genotoxic impurities
-
Feature
Flow chemistry surges forward
The long-discussed technique could help make pharma manufacturing more distributed, finds Andy Extance, and create opportunities for chemists with the right skills
-
Review
The Doctor Who Fooled the World: Andrew Wakefield’s War on Vaccines
The story of the man who created the myth that a vaccine causes autism
-
Business
University team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
-
News
Green light for world’s first Sars-CoV-2 studies that will infect healthy volunteers
UK trials will assess how well Covid-19 treatments work and if vaccines protect against new virus variants
-
Business
Coronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
-
Feature
Drugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
-
Webinar
Physics-based computational modeling applied to the design and optimisation of biologics
Explore how FEP technology (including FEP+) can be applied in protein engineering work
-
Review
The Poison Trials: Wonder Drugs, Experiment, and the Battle for Authority in Renaissance Science
An extremely well-researched monograph containing stories that bear an eerie resemblance to today’s politicised clinical trials
-
Research
Linking chemistry with surgery to detect cancerous cells in situ
Livia Schiavinato Eberlin explains how her team has developed a hand-held device for surgeons that analyses tissue samples on a mass spectrometer mid-operation
-
Opinion
A rough guide to pharma partnership deals
Coronavirus vaccines are driving unusual collaborations with a range of benefits
-
Business
Biggest venture yet of any pharma company into cannabis
Jazz Pharmaceuticals buys cannabinoid therapeutic firm for $7.2 billion, inheriting first plant-derived cannabinoid medicine ever approved by FDA