Medicinal chemistry – Page 18
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BusinessCoronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
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FeatureDrugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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WebinarPhysics-based computational modeling applied to the design and optimisation of biologics
Explore how FEP technology (including FEP+) can be applied in protein engineering work
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ReviewThe Poison Trials: Wonder Drugs, Experiment, and the Battle for Authority in Renaissance Science
An extremely well-researched monograph containing stories that bear an eerie resemblance to today’s politicised clinical trials
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ResearchLinking chemistry with surgery to detect cancerous cells in situ
Livia Schiavinato Eberlin explains how her team has developed a hand-held device for surgeons that analyses tissue samples on a mass spectrometer mid-operation
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OpinionA rough guide to pharma partnership deals
Coronavirus vaccines are driving unusual collaborations with a range of benefits
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BusinessBiggest venture yet of any pharma company into cannabis
Jazz Pharmaceuticals buys cannabinoid therapeutic firm for $7.2 billion, inheriting first plant-derived cannabinoid medicine ever approved by FDA
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BusinessCovid vaccination efforts bolstered by trial results from J&J and Novavax
A miserable January ended with positive news on the vaccine front but new variants added complications
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ArticleAstraZeneca puts academia at the heart of pharma
At the heart of chemical biology are the molecules that make medicines effective and safe for consumers. AstraZeneca harnesses the scientists at the heart of academia to create a healthier world
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NewsOxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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OpinionRuling out the rule of five
Simple calculations for clinical trial success failed to find a winning formula
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NewsDecoding the virus – what we know about Sars-CoV-2 a year on
Scientists have never learnt so much about a pathogen in such a short time
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WebinarHigh-throughput reaction screening for accelerated materials research
Learn how structure-property relationships can be used to re-design reactions or catalysts to achieve a desired activity
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NewsUK abandons school Covid monitoring as testing devices divide public health scientists
Scientists split over use of lateral flow tests as some fear they could actually increase spread of the coronavirus
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ResearchNitrogen radical chemistry sees the light
Daniele Leonori explains how his group is taking inspiration from 30-year-old chemistry to devise shorter syntheses for bioactive compounds
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NewsOld drugs prove their worth against Covid-19 as search continues for life-saving therapies
Thousands of patients have now taken part in trials around the world that have helped sift hope from hype
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BusinessCan chemistry thaw the vaccine cold chain?
Covid-19 has highlighted the challenges of storing vaccines at their proper temperature. Angeli Mehta explores how scientists are trying to protect vaccines from heat degradation
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BusinessVaccine approvals offer hope as global Covid cases surge
A handful of vaccines are now approved and the first doses are being given to patients, with trials for many more candidates nearing completion
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ResearchPFAS exposure found to increase risk of severe Covid-19
Warnings that high levels of per- or poly-fluorinated substances might also reduce the effectiveness of a vaccine