Medicinal chemistry – Page 21
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BusinessCovid-19 vaccine deals risk skewing supply
International accords including Covax aiming to ensure equitable distribution to poorer countries
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WebinarDeveloping small-molecule degraders using chemoproteomics
Discover how chemoproteomics can inform the development of small molecule degraders
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FeatureHuman chemical communication
Nina Notman sniffs out the evidence for human pheromones and chemical cues
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BusinessProtein-based Covid-19 vaccines could overshadow rivals
Although slower to develop, protein-based vaccines are well understood with a strong record of safety and effectiveness
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ResearchDNA-compatible C–H activation method set to benefit drug discovery
Larger and more diverse DNA-encoded libraries on the cards thanks to new tool
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NewsRush to approve Covid vaccine prompted by politics may end in disaster
Push by governments to pass a vaccine without appropriate evidence could damage fight against virus
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BusinessRussian Covid-19 vaccine data raises questions
Suspected data manipulation or fabrication casts shadows over safety trial report for hastily-approved Sputnik V
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NewsRussian opposition leader was poisoned with Novichok agent
German chancellor Angela Merkel says Russia has ‘serious questions’ to answer after tests confirm presence of nerve agent in Alexei Navalny’s bloodstream
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OpinionFacing the challenge of vaccine trials
Russia’s Covid-19 gamble is a stark contrast to even accelerated clinical programmes
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BusinessRussian vaccine launch shocks scientists
Sputnik V to be approved without large human trial data
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ResearchMass spectrometry and augmented reality guide tumour removal in real time
Colour pixels help surgeons differentiate between cancerous and healthy tissue
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BusinessEncouraging signs from initial Covid-19 vaccine trials
Human trials deliver positive immune responses, while primate challenge studies suggest protection is possible
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FeatureWhy is cystic fibrosis so hard to treat?
Claire Jarvis talks to the scientists trying to find new drugs to treat the inherited lung condition
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ResearchTranslating snail venom research from beach to bench and beyond
Meet Mandë Holford, an interdisciplinary scientist following tangents that arise when exploring the molecular-level workings of venom peptides
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PodcastFavipiravir
Originally developed to treat flu and marketed in Japan as Avigan, promising Covid-19 trial results have seen countries stockpiling this medication by the millions
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OpinionQuestioning European policy on alkyl mesylate impurities
Policies based on false hypotheses can persist in spite of overwhelming contradictory data
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WebinarIlluminating research with the LightOx PhotoReact 365 benchtop photoreactor
Learn about the LightOx PhotoReact – a benchtop photoreactor enabling reproducible irradiation for photochemical and photobiological applications
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PodcastTannic acid
Tannic acid in green acorns can kill wild animals and livestock, but you can prevent poisoning with pannage pigs
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BusinessAppeals court cuts damages further in glyphosate cancer case
Judgment retains verdict that Bayer-Monsanto’s herbicide caused US man’s cancer