Medicinal chemistry – Page 22
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ResearchCommon inactive drug ingredients not as inert as thought
38 out of 639 excipients tested interact with toxicity-related proteins, some reaching levels that might produce unwanted effects
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OpinionLooking beyond the next wave
We need to apply lessons from Covid-19 to tackle antimicrobial resistance and climate change
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NewsHand-powered centrifuge setup can diagnose Covid-19 for just a dollar a test
$5 centrifuge based on children’s toy part of raft of cheap technologies that can detect the virus in saliva in remote locations
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ResearchAlgorithm predicts mortality of Covid-19 patients from blood biomarkers
Artificial intelligence tool to help doctors prioritise treatment
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NewsDoes hydroxychloroquine still have a role to play in this pandemic?
Touted as a wonder drug by some its star now appears to be on the wane
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BusinessWhat are the risks of fast-tracking a Covid-19 vaccine?
Condensing timelines from years to months inevitably involves compromises
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OpinionGhanaian biochemistry TV star Marian Addy
Marian Addy was the first female science professor in Ghana, who studied herbal medicine – and was a TV star
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NewsSuit of iron turns sperm cells into spermbots
Microrobots that swim under the influence of a magnetic field could one day be used to deliver drugs
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BusinessScrambling and gambling to scale up Covid-19 medicines
Organisations work towards making billions of doses of products not yet proven to work
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OpinionDragons of immunology
Anti-inflammatories like dexamethasone are triumphs amid the pitfalls of the immune system
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ResearchComputational method challenges NMR metabolomics dogma
Macromolecule signal suppression without the loss of quantitative small molecule information finally achieved with mathematical trick
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NewsExplainer: how is the vaccine pipeline for Covid-19 looking?
The race to develop a vaccine is almost six months old. Who’s in the lead?
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PodcastDexamethasone
News that this cheap, ubiquitous steroid drug may reduce deaths in Covid-19 cases has been greeted with cautious optimism
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NewsCovid-19 is forcing pharma to rethink clinical trials
Drug trials have become a casualty of Covid-19, but the pandemic is also prompting change
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OpinionMaking the right call on dexamethasone
The way we do things in research has to change in life or death situations
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WebinarWL Gore: Optimising production processes with Design of Experiments
Learn how WL Gore use definitive screening designs to analyse multiple factors and optimise production processes
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ResearchUnprecedented biosynthetic transformation found to connect antibacterial polyketides from ant microbiome
Study identifies enzymes that convert flat fasamycins into three-dimensional formicamycins
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ResearchAlgorithm devises synthetic contingency plans for Covid-19 drug
Retrosynthesis software tool can identify multiple synthetic routes that use inexpensive and diverse starting materials while avoiding patented methods
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NewsCaution urged as scientists await results of trial that finds steroid cuts Covid-19 deaths
Claims that 60-year-old drug dexamethasone dramatically lowers fatality rate of seriously ill Covid-19 patients await peer review
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FeatureThe difficulties of drugging our brains
Following the withdrawal of many large pharma companies from central nervous system research, Andy Extance finds new drug development patterns are emerging