Medicinal chemistry – Page 23
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PodcastCimetidine
Mike Freemantle introduces the peptic ulcer treatment cimetidine, which – as Tagamet – became the first blockbuster drug
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ResearchMethod that yields oxygen-18-enriched alcohols set to bolster drug studies
Mitsunobu-based protocol is simple alternative to limited and lengthy methods
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OpinionCollaboration is key to AI-aided drug discovery
The AI Cures project shows how artificial intelligence can assist the search for a cure for Covid-19
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ResearchRespiratory viruses detected in 30 minutes with the help of a smartphone
$50 smartphone accessory could be adapted for Covid-19
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BusinessDeveloping antiviral mask technology in a pandemic
Surface chemistry strategies play a pivotal role in personal protective equipment that can neutralise the Sars-CoV-2 virus
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ArticleOptimising biotech processes
Fujifilm Diosynth Biotechnologies achieve both speed and scale through designed experiments
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PodcastFexinidazole
The World Health Organisation hope to eradicate sleeping sickness within our lifetimes. Jamie Durrani looks at a drug that may make it possible.
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ResearchDatabase offers another way to search for drugs – by activity not structure
Dataset offers new way for biomedical researchers to identify potential drug candidates
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FeatureDrugging the gut microbiome
Treating the bacteria that live inside us can improve our own health. Clare Sansom meets our tiny friends
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WebinarTeaching Design of Experiments to chemists: lessons from Imperial College London
First-hand experience from Imperial College London: Join us to learn about the importance and efficient implementation of a DoE training program in chemistry
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OpinionCovid-19 poses trust issues for science
The pandemic is proving the importance of public trust in science
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PodcastDMT – Dimethyltryptamine
Georgia Mills investigates the psychoactive found in ayahuasca that may mirror near-death experiences
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NewsVaccine manufacturing centre to be rushed into service a year early by UK government
Injection of new funding will mean centre opens in 2021 as licensing deal also agreed to boost vaccine capabilities
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BusinessHow Covid-19 is changing drug manufacturing
Catalent is adapting, focusing on employee safety and supply chain security
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BusinessThis little Crispr went to market
Gene editing technology heading towards commercial reality in pharmaceuticals, food and organ transplant
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OpinionAlice Ball’s treatment for leprosy
Nina Notman tells the overlooked story of historic African-American chemist Alice Ball who developed the first partially-effective treatment for leprosy
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NewsEfforts to combat Covid-19 in India hit by imported reagent shortages
Low testing rates and supply problems have led to a search for alternatives
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OpinionHopes and fears for remdesivir
Available resources for testing coronavirus treatments need to be used wisely
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OpinionDoes the drug work, or not?
Coronavirus trials reveal the murky reality of disentangling compounds’ effects on human biology
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BusinessMicropore Technologies’ model membranes make exact emulsions
Solving scalability issues to control particle size without high-shear mixing