Medicinal chemistry – Page 23
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OpinionRuling out the rule of five
Simple calculations for clinical trial success failed to find a winning formula
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NewsDecoding the virus – what we know about Sars-CoV-2 a year on
Scientists have never learnt so much about a pathogen in such a short time
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WebinarHigh-throughput reaction screening for accelerated materials research
Learn how structure-property relationships can be used to re-design reactions or catalysts to achieve a desired activity
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NewsUK abandons school Covid monitoring as testing devices divide public health scientists
Scientists split over use of lateral flow tests as some fear they could actually increase spread of the coronavirus
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ResearchNitrogen radical chemistry sees the light
Daniele Leonori explains how his group is taking inspiration from 30-year-old chemistry to devise shorter syntheses for bioactive compounds
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NewsOld drugs prove their worth against Covid-19 as search continues for life-saving therapies
Thousands of patients have now taken part in trials around the world that have helped sift hope from hype
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BusinessCan chemistry thaw the vaccine cold chain?
Covid-19 has highlighted the challenges of storing vaccines at their proper temperature. Angeli Mehta explores how scientists are trying to protect vaccines from heat degradation
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BusinessVaccine approvals offer hope as global Covid cases surge
A handful of vaccines are now approved and the first doses are being given to patients, with trials for many more candidates nearing completion
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ResearchPFAS exposure found to increase risk of severe Covid-19
Warnings that high levels of per- or poly-fluorinated substances might also reduce the effectiveness of a vaccine
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BusinessPharmaceuticals roundup 2020
Alongside the race for Covid-19 treatments and vaccines, the industry has maintained momentum
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WebinarFaster drug discovery and optimisation with physics-based computational methods
Learn how physics-based computational methods, such as Free Energy Pertubation (FEP) calculations, can speed up the drug discovery and lead optimisation
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NewsMystery illness that hospitalised hundreds in India stumps health experts
Authorities are looking at pesticide contamination of food and water as well as heavy metals
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ResearchExplainer: How would UK science be affected by a no-deal Brexit?
Access to EU science schemes, freedom of movement and student places are all expected to be disrupted
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ResearchChemists tame shamanic addiction treatment
Animal experiments show modified structures remove ibogaine’s hallucinogenic and heart-harming effects
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BusinessCybercriminals target Covid-19 vaccines
Officials in the UK and US warn of threat from cyber-attacks that steal data related to Covid-19 vaccines and aim to disrupt the supply chain
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Feature2020: the year the world changed
Andy Extance discovers how scientists around the world have responded to the pandemic, working on solutions from drugs and vaccines to hand sanitiser and PPE
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ResearchFluorescent molecule breaks size record for green-emitting dyes
Study identifies 14-atom fluorophore with range of potential biological applications
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BusinessPfizer–BioNTech vaccine gains emergency approvals in US, Canada and beyond
UK begins vaccinating vulnerable populations after early authorisation
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ResearchAnimal tests reveal synthetic decoy protein protects against coronavirus
Protein designed from scratch binds Sars-CoV-2 with high affinity and specificity
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BusinessUK grants Pfizer–BioNTech Covid-19 vaccine emergency approval
Regulators around the world working towards accelerated decisions on vaccine data