Medicinal chemistry – Page 24
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BusinessFDA freezes foreign facility inspections amid coronavirus pandemic
US regulator will rely on border checks and shared data, but some approval processes may be delayed
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BusinessCoronavirus pandemic will disrupt international supply chains
Halted production and transport restrictions are straining industries that rely heavily on China for supplies
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BusinessRNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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ResearchCheating bacterium becomes antibiotic-tolerant at expense of other species
Coexistence triggers counterintuitive antibiotics response in bacteria, which could be used to tackle hardy species
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ResearchMetal complexes outperform organics in antimicrobial analysis on crowdsourced compounds
Could this study prompt drug developers to rethink their reluctance to making metal-based pharmaceuticals?
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OpinionFit to 3D print
Construction from the bottom up has benefits but users must proceed with caution
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ResearchAI tool screens 107 million molecules, discovers potent new antibiotics
Deep learning approach could help in fight against drug-resistant bacteria
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NewsOpen data and genomics are at the forefront in battle to control coronavirus
Efforts to tackle the virus have seen unprecedented cross-border collaboration
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ResearchDetailed 3D coronavirus spike map offers hope for vaccine development
Structure determined at ‘remarkable’ speed in little over a month
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OpinionTwo heads are better than one
Bifunctionals show that sometimes simply tethering two useful molecules together unlocks some useful activity
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FeatureAdjuvants: vaccines’ hidden helpers
Anthony King examines a crucial part of vaccines that can significantly boost their performance, but which often go unrecognised
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BusinessThe race to fight coronavirus
While genome sequences enable testing and vaccine efforts, companies are donating existing antiviral drugs to explore repurposing
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ArticleTransforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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ResearchChemists complete synthesis of molecule ‘at the limits of complexity’
Synthesis of canataxpropellane paves the way to biological studies
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ResearchFirst Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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ResearchTest for antibiotic resistance genes provides answers within an hour
Whole blood method for diagnosing bacterial infections has unprecedented speed and sensitivity
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ResearchWarning that 3D printing pills can stop drugs working
Photoreactive monomers need close scrutiny for production of polypills
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FeatureThe search for cancer vaccines
Claire Jarvis looks at ongoing work to prevent the disease – and convince a sceptical community of their seriousness
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OpinionThe hunt for a killer stalking vapers
Vaping deaths in the US became a whodunnit as chemistry was called upon to track down the culprit