Medicinal chemistry – Page 27
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ResearchElusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions
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PodcastSodium fluoroacetate
The controversial killer compound – also known as 1080 – being used to protect New Zealand’s native wildlife
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OpinionEmbracing structural disorder
Medicinal chemists need to overcome their fear of fuzzy proteins
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NewsUS children’s hospital takes delivery of one of world’s most powerful NMR spectrometers
Instrument offers unprecedented opportunities to study disease development
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NewsDeaths from vaping-linked lung disease in US connected to vitamin E additive
Tocopheryl acetate implicated in 380 cases of severe lung disease and six deaths
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ReviewMescaline: A Global History of the First Psychedelic
A story about the people who harvested, used, abused, regulated and investigated the mind-altering drug
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FeatureStem cell hype
Many clinics around the world offer unproven treatments, while genuine therapies are slowly making their way through trials. Anthony King reports
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PodcastDomoic acid
The marine toxin that drives animals crazy and might have inspired one of Alfred Hitchcock’s most famous films
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PodcastBoric acid
Mike Freemantle revisits battlefield surgery to investigate boric acid, a key part of Dakin's antiseptic solution used extensively in the first world war
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ResearchRetrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
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PodcastAmygdalin & Laetrile
Patrick Hughes delves into the molecule at the centre of a decades-old cancer treatment conspiracy theory
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ResearchWood microfluidics carve out a niche
Teflon-coated wood devices perform as well as plastic equivalents but face some challenges before they can realise their clinical and sustainable potential
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NewsConcerns raised over ‘regrettable’ BPA substitutions
Research indicates chemicals used as alternatives to bisphenol A in polycarbonate plastics and epoxy resins aren’t always safer
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NewsData manipulation casts shadows on Novartis gene therapy
Manufacturing problems with other new medicines highlight difficulty of developing advanced treatments
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OpinionMargaret Brimble: 'Spiroketals are my favourite molecules'
The New Zealand chemist on careers, creativity and why everything just has to be blue
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ArticleAccurate temperature control achieving big results, on a small scale
Radleys’ compact reaction station brings accurate temperature control to chemical scientists managing small-scale experiments
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OpinionAre new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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ResearchModified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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