Medicinal chemistry – Page 30
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NewsNorthwestern opens largest biomedical building of any US university
Chemistry sits atop Northwestern University’s new 12-story interdisciplinary biomedical centre
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PodcastAzidothymidine
The first drug approved in the US to treat Aids required a completely new approach to clinical trials – Frances Addison explores the history of azidothymidine
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ResearchGlucose-regulating nanogel keeps blood sugar in the sweet spot
System prevents hyperglycemia in rats by acting like an artificial liver
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OpinionIs this a golden age of new drug classes?
A host of new treatment modes are hitting the clinic and the market
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ResearchSaliva test uses surface imprinting to recognise Zika
Sensor matches surface roughness of its electrode with Zika’s dimensions and generates results within 20 minutes
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ResearchSpore shell acts as sunscreen for light-sensitive antibiotics
Polymer capsule that protects and preserves antimicrobial compound could aid fight against multi-drug resistant pathogens
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PodcastAmantadine
Katrina Krämer investigates how one of the smallest small molecule drugs around saved Jeanna Giese's life
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ResearchLaser technique watches how implants release drugs
Laser induced breakdown spectroscopy continues to diversify its applications
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WebinarMiniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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BusinessUS finalises guidance on biosimilars
Regulator clarifies requirements for allowing substitution between products
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ResearchTrefoil knots steer cancer drug leads in fresh direction
Chemists look to links and knots in the search for new cancer therapies
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FeatureChanging the locks
Designer receptors help understand cellular signals and could treat epilepsy and Parkinson’s disease, but need new tools, finds Andy Extance
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PodcastMethylphenidate (Ritalin)
Jamie Durrani diverts his attention to the rise of Ritalin, a drug first identified as a way of improving tennis performance
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ArticleHow biologics have changed the rules for pharma
The impact of the latest generation of drugs for the healthcare industry
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ResearchSwitching to sulfur stops deadly bacteria growth
Modified sugar prevents growth of Clostridium difficile while retaining useful properties
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PodcastLimulus Amebocyte Lysate
Frances Addison takes a look at the discovery that brought horseshoe crabs to the heart of the pharmaceutical industry
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OpinionThe case for South Africa as the next pharma hub
Flow chemistry could drive regional manufacturing in Africa
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FeatureMalaria no more?
Efforts to cure malaria have been going on for hundreds of years. Clare Sansom looks at some of the latest – and most innovative
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PodcastLevothyroxine
Kit Chapman investigates the drug that has been one of the top five prescription medications in the UK every year for the last two decades