Medicinal chemistry – Page 32
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Research
Fluorinated compounds in cosmetic products
Moisturisers, shaving foam and foundation investigated as sources of per- and polyfluoroalkyl substances
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Research
Erythropoietin benefits from controlled sugar-coating
Click chemistry allows glycosylation at virtually any synthetic stage
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Business
Sartan drug contamination brings cancer uncertainty
Levels of nitrosamines and other carcinogens in affected tablets of valsartan and related drugs similar to smoking 20 cigarettes a day
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News
X-ray crystallographer to oversee Rosalind Franklin Institute
Structural biologist James Naismith to become first director of UK’s new national life sciences institute
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Research
Wearable sensor checks blood alcohol content using sweat
Device shows how sweat could be used as a non-invasive source of biochemical information
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Business
Breaking the silence of RNA interference drugs
A wave of treatments is set to follow the first approval of an RNAi therapy
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Research
Scorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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Review
Bitter Pills: The Global War on Counterfeit Drugs
Muhammad Zaman’s book gives an account of the challenges facing drug regulators worldwide
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Business
Transforming PET imaging with silicon
Fuzionaire Diagnostics can add Si–18F radiolabels to a variety of molecules quickly, easily and cheaply
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Review
How to Change Your Mind: The New Science of Psychedelics
Journalist Michael Pollan’s 9th book is a fascinating history of psychedelic drugs.
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Research
Hidden gene cluster unearthed to reveal antibacterial natural product
Scientists encourage soil microorganisms to express themselves
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Podcast
Furanocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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Research
First oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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Research
Deep tissue penetration allows fluorophore to guide tumour surgery
Bioimaging probe excited by longer wavelengths of light but doesn’t suffer from long-term retention in the immune system
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Opinion
Passing through checkpoints
A new breed of cancer treatments highlights what’s possible when industry concentrates its efforts
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Research
New peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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Opinion
The potential of promiscuity
Nobel recognition for a concept whose benefit to humankind is far from being truly realised
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Research
Milk protein could alleviate metallic taste following chemotherapy
Study indicates that a lactoferrin supplement could treat taste and smell irregularities experienced by cancer patients
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Business
Cancer immunotherapy spreads rapidly
New approvals and expanded use for checkpoint inhibitor drugs illustrate the power of Nobel-winning science