Medicinal chemistry – Page 34
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ResearchHidden gene cluster unearthed to reveal antibacterial natural product
Scientists encourage soil microorganisms to express themselves
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PodcastFuranocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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ResearchFirst oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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ResearchDeep tissue penetration allows fluorophore to guide tumour surgery
Bioimaging probe excited by longer wavelengths of light but doesn’t suffer from long-term retention in the immune system
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OpinionPassing through checkpoints
A new breed of cancer treatments highlights what’s possible when industry concentrates its efforts
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ResearchNew peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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OpinionThe potential of promiscuity
Nobel recognition for a concept whose benefit to humankind is far from being truly realised
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ResearchMilk protein could alleviate metallic taste following chemotherapy
Study indicates that a lactoferrin supplement could treat taste and smell irregularities experienced by cancer patients
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BusinessCancer immunotherapy spreads rapidly
New approvals and expanded use for checkpoint inhibitor drugs illustrate the power of Nobel-winning science
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ResearchNanopore sensors make breakthrough in monitoring health and disease
Biosensor simultaneously measures metabolite biomarkers in bodily fluids
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FeatureHow chemical evolution took the 2018 chemistry Nobel prize
Emma Stoye has the full story of how Frances Arnold, George Smith and Greg Winter put evolution to work in the lab
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OpinionThe projects drug companies wish they’d never started
Failures are common in drug research, but some are bigger than others
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ResearchNanoparticles offer extensive new cure for snakebites
Treatment neutralises venom, reducing tissue damage
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BusinessCleaning up clinical trials
Campaigns to enforce complete and correct reporting of trial data are beginning to take hold
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NewsWhat is directed evolution and why did it win the chemistry Nobel prize?
If you’ve got questions about yesterday’s chemistry Nobel prize then we’ve got answers
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NewsWhat is 'checkpoint therapy' and why did it win the medicine Nobel prize?
James Allison and Tasuku Honjo released the ‘brakes’ on our immune system to combat cancer
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NewsImmune-stimulating cancer treatment takes 2018 medicine Nobel
James Allison and Tasuku Honjo receive science’s highest honour for discovering how cancer stops immune cells from attacking
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ResearchHealthy animals mimic body odour of sick companions
Sniffer mice and chemical analysis suggest that sickness odours are contagious