Medicinal chemistry – Page 34
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OpinionFeeding the confusion
When it comes to working out what foods do to our bodies, mostly we just don’t know
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FeatureThe quest to cure HIV
Although HIV–Aids can now be managed quite well with antiretroviral drugs, there is still no cure. Anthony King talks to the scientists trying to find one
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BusinessUS approves first RNA interference drug
Alnylam’s Onpattro (patisiran) can treat a rare hereditary disease by silencing a specific gene
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ResearchBismuth drugs kill bacteria by disrupting metabolism
Scientists throw kitchen sink of omics techniques at understanding complicated response of prevalent human pathogen to bismuth drug
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FeatureFrom folklore to pharmacy
Although many drugs have in the past come from plants, Hayley Bennett discovers that it’s hard work getting them approved today
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NewsEPA move could bring asbestos back in America
Health advocates fret at US environment agency’s proposal to make ‘new uses’ of asbestos-containing products legal, but EPA says not to worry
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PodcastThe Beautiful Cure by Daniel Davis – Book club
Immunologist Daniel Davis reveals the complexities of the human immune system
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ReviewThe Beautiful Cure: Harnessing your body's natural defences
The human body’s response to disease is fiendishly complex but endlessly fascinating
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BusinessVaccine scandal and heart drug recall show China’s pharma struggles
Fifteen arrests amid evidence of bribery related to vaccines, despite new standards and penalties for fraud
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BusinessNovartis exit from antibiotics a setback for race against resistance
Experts say business models must change to halt big pharma exodus
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ResearchArtificial intelligence seeks out new anticancer drugs
A combination of machine learning methods yields promising results for drug discovery
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BusinessTrump coaxes big promises from big pharma
Several drug industry giants are now pledging to freeze price increases in the US, but some suggest the movement is a publicity stunt or worse
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ResearchAI tool could save on animal tests
Algorithm could also help unravel poisoning or environmental contamination cases
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NewsNovichok poisoning breakthrough as original container found
Decontamination efforts continue as source of nerve agent found in victim’s house
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PodcastCannabidiol
The story of Charlotte Figi, Dravet syndrome and the cannabis compound controlling her condition
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Opinion'If I'd discovered metformin, I'd have tossed it aside...'
Trusting our intuition too strongly highlights how little we know about chemical activity