Medicinal chemistry – Page 36
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ResearchNew theory for why lithium helps bipolar patients
Molecular insight could help researchers design mood stabilisers with fewer side effects
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NewsChemical weapons watchdog confirms UK’s nerve agent findings
Independent international investigators verify that a Novichok agent was used in attempted assassination of former Russian spy in Salisbury
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PodcastAcetylcysteine
How a versatile drug that helps manage lung conditions and treat paracetamol overdose found itself at the centre of a cycling scandal
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BusinessNovartis’ $8.7bn AveXis deal shows gene therapy appeal
Acquisition indicates the value of potentially permanent cures for inherited diseases
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ResearchArtificial blood reaches the feline frontier
Space crystals of serum proteins help scientists make a red blood cell substitute for cats
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ResearchJelly implant keeps an eye on body oxygen levels
A soft hydrogel implant – the first of which has survived in the foot of its inventor for four years – could detect circulatory problems that end in amputations
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ResearchSolving the crystal maze
Workflow swaps gut feelings for data when designing continuous crystallisation processes
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NewsGetting a better grasp of manganese to fight flu
A drug that can hold onto two metals atoms rather than just one becomes 1000 times more potent at knocking out a flu virus enzyme
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BusinessFit for repurpose
Drugs that can be used for new indications offer a potentially cheaper pathway – but only if the investors can recoup their costs
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ResearchBacteria churn out a million potential protein drugs
Modified bacteria produce enormous library of macrocycles, one of which inhibits a HIV protein
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NewsProblems of an ageing population addressed by extra UK funding
£300 million from fund will go towards research on dementia and personalised medicine
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FeatureCuba: socialism, cigars and biotech
Nina Notman learns how biotechnology could potentially overtake cigars as Cuba’s most famous export
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ArticleIs industry ready for the serialisation shake-up?
The regulation few outside of pharma have heard about
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ArticleFive innovative technologies for health
How do healthcare products get from academic or start-up labs to the clinic? With a little help from places like the Centre for Process Innovation
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ArticleDriving pharmaceutical innovation
Making drugs is neither easy nor cheap – but catalysts, flow chemistry and a knowledge of intermolecular interactions can help
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ArticleDissolving insoluble drugs
How spray drying can help with solubility and bioavailability challenges in drug development
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ArticlePlatinum metal complexes in medicine
The history of cisplatin, the drug that is still the gold – or should that be platinum? – standard in cancer drugs
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ArticleBiosensors, wearables and virtual biotech
In a world that is racing ahead with new technologies, has the drug development process distanced itself from the patients it ultimately provides for?
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ArticleWhy biocatalysis is so on trend
Biocatalysis has come a long way from just beer – there’s an enzyme for nearly everything