Medicinal chemistry – Page 38
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ResearchBacteria churn out a million potential protein drugs
Modified bacteria produce enormous library of macrocycles, one of which inhibits a HIV protein
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NewsProblems of an ageing population addressed by extra UK funding
£300 million from fund will go towards research on dementia and personalised medicine
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FeatureCuba: socialism, cigars and biotech
Nina Notman learns how biotechnology could potentially overtake cigars as Cuba’s most famous export
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ArticleIs industry ready for the serialisation shake-up?
The regulation few outside of pharma have heard about
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ArticleFive innovative technologies for health
How do healthcare products get from academic or start-up labs to the clinic? With a little help from places like the Centre for Process Innovation
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ArticleDriving pharmaceutical innovation
Making drugs is neither easy nor cheap – but catalysts, flow chemistry and a knowledge of intermolecular interactions can help
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ArticleDissolving insoluble drugs
How spray drying can help with solubility and bioavailability challenges in drug development
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ArticlePlatinum metal complexes in medicine
The history of cisplatin, the drug that is still the gold – or should that be platinum? – standard in cancer drugs
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ArticleBiosensors, wearables and virtual biotech
In a world that is racing ahead with new technologies, has the drug development process distanced itself from the patients it ultimately provides for?
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ArticleWhy biocatalysis is so on trend
Biocatalysis has come a long way from just beer – there’s an enzyme for nearly everything
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ArticleThe ever-increasing attraction of biologics
Biologics promise targeted treatments for a range of conditions – if we can overcome the technological challenges
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FeatureThe chemistry of the microbiome
Our gut bacteria are carrying out chemistry on our behalf, but without us knowing much about it. Now, scientists are starting to examine their enzymes
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FeatureThe antibiotic countdown
Where are the next generation of antibiotics going to come from? Clare Sansom looks at the pipeline
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ResearchAntimalarial plant's chlorophyll catalyses drug synthesis
New ‘green’ method makes malaria-fighting artemisinin’s synthesis faster and cheaper with industrial production planned for 2021
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NewsTracker to name and shame for failure to report clinical trial results
Developers of online tool hope that it will improve accountability
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NewsFDA approves new way to make medical imaging isotope
System will be the US’s first domestic source of molybdenum-99 for 30 years
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BusinessBMS stimulates cancer drug hopes with giant collaboration
Immunooncology pioneer will pay up to $3.6bn in hope Nektar drug will help non-responders
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NewsIllegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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FeatureArtificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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ResearchAntibiotic analogue puts researchers on path to ending herbicide drought
Research flags DNA gyrase as a new target for pesticides