Medicinal chemistry – Page 38
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ReviewMore molecules of murder
Aurora Walshe reviews a book that walks the line between morbid and fascinating
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ResearchFood additive may have given deadly bacterium its chance
Trehalose sugar offers competitive advantage to virulent strains of gut bacterium C. difficile
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ResearchSuzuki–Miyaura–hydrogenation targets 3D drugs
Researchers design a new pathway to make sp3 enriched drug molecules
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BusinessPharmaceuticals roundup 2017
Political influence has strongly shaped industry activity in the past year
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BusinessSanofi ordered to pull dengue vaccine
Philippines wants French drugmaker to cover immunisation program costs
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OpinionChanging the reproducibility rulebook
It pays to know when taking shortcuts is acceptable, and which it’s safe to take
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FeatureFrom venoms to medicine
Venoms are a treasure trove of peptides that may provide a bounty of novel painkillers
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NewsMisconduct scandal hits UK forensics lab
Thousands of criminal cases may have to be revisited due to botched drug tests
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BusinessTargeting rare diseases
Is working on genetic mutations that affect only a few in every thousand people risky?
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ResearchCosmetic and perfume sales staff exposed to high phthalate levels
Exposure poses potential risks for pregnant women working in retail
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FeatureStaying one step ahead of the game
Clare Sansom examines the need for agile drug development when tackling emerging viral disease outbreaks
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ResearchTagging drugs with heavy hydrogen made as easy as flicking a light switch
Photoredox reaction simplifies metabolism studies by swapping hydrogen for deuterium or tritium
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BusinessChuck Norris versus gadolinium
US action star is suing 11 drug firms for $10m, claiming his wife was poisoned by gadolinium from her MRIs
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BusinessGSK’s shingles vaccine gets thumbs up in North America
Inoculation slated to be a blockbuster
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OpinionNatural selection
Bioactive compounds don’t just inspire new synthetic strategies, they’re also the ultimate test
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NewsNew guidelines to standardise toxicity testing for nanomaterials
OECD hopes methods will ensure companies are singing from same song sheet on nanosafety
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OpinionRise of the biologics
Antibodies, RNA and gene therapy don’t necessarily compete with small molecule drugs – and they all rely on chemistry