Medicinal chemistry – Page 40
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WebinarCurrent topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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FeatureEnvironmentally benign by design
The challenge of designing drugs with biodegradability in mind
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ResearchSingle-cell imaging spots resistant infections in less than half an hour
Microfluidic device allows speedy susceptibility testing so the right antibiotic can be given
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NewsUS chemical lobby welcomes congressional probe of cancer research agency
House panel requests an NIH briefing about why it didn’t publish glyphosate study results
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PodcastIndometacin
A popular prescription pill that helps to keep gout and other arthritic conditions under control
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ResearchStructural sleuthing salvages superbug slayer
Combining ‘assembly line’ synthesis, spectroscopy and computational predictions solves stereochemistry riddle
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NewsMillions of 'bad eggs' recalled in contamination scandal
Investigations into how chicken eggs across Europe came to contain fipronil are still ongoing
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BusinessBristol-Myers Squibb bags immunotherapy unicorn
Deal will add to pharma giant’s cancer portfolio
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ReviewExhibition: Open for discovery
The Francis Crick Institute’s first exhibition showcases its scientists’ research
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ResearchPlotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
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BusinessAstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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BusinessNovartis coasts towards first CAR-T approval
Unanimous recommendation for CTL019 ahead of October decision builds confidence in T-cell genetic reprogramming
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ResearchDietary supplement poisoning every 24 minutes in the US
275,000 calls concerning supplements were made to poison centres between 2002 and 2012
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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ResearchSimplified structure eases antibiotic synthesis
New analogues of the potent antibiotic teixobactin could be instrumental in the fight against multi-drug resistant pathogens
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ResearchResponsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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OpinionMaking enough of a difference
What if the needle in the drug development haystack ends up being too small to be useful?
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BusinessFDA approves first sickle cell drug in almost two decades
Glutamine-based drug is the first approved for children over 5
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BusinessAmplifying intelligent drug design
This year’s Chemistry World Entrepreneur of the year is Andrew Hopkins of start-up Exscientia and the University of Dundee, UK
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NewsEuropean ‘One Health’ plan aims to curb antimicrobial resistance
Action plan treats human and animal health as interconnected