Medicinal chemistry – Page 41
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BusinessTakeda tightens focus on core areas with multiple deals
Japanese firm is remodelling its R&D efforts through collaboration and licensing deals, and selling off non-core businesses
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ArticlePharma supply chains pick up pace
Contract suppliers are increasingly important in reducing time to market
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ArticleIn-house training speeds up metabolism
Business plugs DMPK skills gap to improve drug discovery
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FeatureThe rising tide of 'legal highs'
Andy Extance investigates the chemistry that has helped recreational drugs evade the law, and its consequences
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ResearchGut bugs hijacking our signalling could treat disease
Gastrointestinal microflora found to produce a profusion of molecules that can affect human health
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FeatureArsenic and rice - a growing problem?
Hayley Bennett highlights rice’s natural affinity for arsenic and what researchers are doing about it
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OpinionSolving the technetium medical isotope shortage
The UK has a solution to the potential shortage of technetium-99m – but that’s no reason to be complacent about leaving Euratom
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ResearchFluorescent test strip detects deadly phosgene gas
Portable test checks for industrial gas leaks and chemical attacks
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OpinionMake room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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WebinarCurrent topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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FeatureEnvironmentally benign by design
The challenge of designing drugs with biodegradability in mind
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ResearchSingle-cell imaging spots resistant infections in less than half an hour
Microfluidic device allows speedy susceptibility testing so the right antibiotic can be given
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NewsUS chemical lobby welcomes congressional probe of cancer research agency
House panel requests an NIH briefing about why it didn’t publish glyphosate study results
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PodcastIndometacin
A popular prescription pill that helps to keep gout and other arthritic conditions under control
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ResearchStructural sleuthing salvages superbug slayer
Combining ‘assembly line’ synthesis, spectroscopy and computational predictions solves stereochemistry riddle
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NewsMillions of 'bad eggs' recalled in contamination scandal
Investigations into how chicken eggs across Europe came to contain fipronil are still ongoing
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BusinessBristol-Myers Squibb bags immunotherapy unicorn
Deal will add to pharma giant’s cancer portfolio
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ReviewExhibition: Open for discovery
The Francis Crick Institute’s first exhibition showcases its scientists’ research
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ResearchPlotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
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BusinessAstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer