Medicinal chemistry – Page 43
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NewsAlzheimer’s disease: have drug developers been on the wrong track?
Dementia drug developers urged to look beyond amyloid
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PodcastAdamantane
Brian Clegg introduces a crystalline hydrocarbon that isn’t as tough as it sounds, but is the basis of a wide range of medicines
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ResearchCrystal structure lifts lid on LSD’s secrets
Structure of hallucinogen bound to a human serotonin receptor could explain LSD’s potent and long-lasting effects
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NewsVaccine coalition to target emerging infectious diseases
Fund attempting to raise $1 billion to develop vaccines before an epidemic strikes
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ResearchPersonalised medicine boost as cancer drug monitored in real-time
Aptamer-based sensors can track levels of small molecules in rats as the go about their business
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BusinessTaming vaccines with chemistry
Vaxxilon aims to simplify vaccine development by replacing biological components with well-defined synthetic molecules
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ResearchAncient whirligig toy inspires cheap, modern centrifuge
People-powered centrifuge can separate blood samples in minutes
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NewsFears that gene-editing cancer trials are premature
Warnings from geneticists that Crispr trial failures could knock promising technique’s prospects
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ResearchRoadkill: new molecules at the side of the road
Wild animals run down on the roads can open surprising doors for opportunistic biochemists
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FeatureNew opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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FeatureIntracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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ResearchChemoluminescent nanoparticles detect multiple deadly viruses in one go
A detection system can test for multiple viruses in one sample
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ResearchDiamonds to track down origins of diseases of ageing
Fluorescent nanodiamonds reveal the inner workings of neurons
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OpinionHow much does fashion influence chemists?
Is that new reaction the next Nobel-worthy breakthrough, or just a flash in the pan?