Medicinal chemistry – Page 44
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Podcast
Bromodeoxyuridine
Kat Arney illuminates the story of a molecular ‘highlighter pen’ for growing cells
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Opinion
Restarting the mental health pipeline
The lack of UK investment in new drugs for mental health disorders is a problem – but the tide may be about to turn
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Careers
The trials and tribulations of drug discovery
The many pitfalls medicinal chemists face when creating a new drug
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Research
Poison dart frog toxin made in mirror image
Toxin’s non-natural enantiomer offers new tool to probe nerve disorders
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Podcast
Benzoyl peroxide
The blondest blonde, the whitest smile, the clearest complexion – all from one essential compound
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Feature
Personalised skincare
Nina Notman explores some of the latest scientific approaches skincare companies are using in the quest to develop high-earning anti-ageing cosmetics
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Research
Dibrominated tag helps identify new natural products
New substance allows researchers to find new aldehyde- and ketone-containing natural products
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News
WHO cancer agency criticised for outdated chemical risk methods
Criticism of carcinogenicity assessments that place processed meat in the same category as mustard gas
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Podcast
PARP: Poly (ADP-ribose) polymerase
Kat Arney explains how a protein that repairs broken DNA holds the key to killing cancer cells – but only if you stop it from doing its job
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Opinion
Regulatory tightropes
When lobbying and marketing clash with scientific evidence, regulators walk a fine line
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Opinion
Putting chemistry back in biology
The chemical nature of biomolecular interactions can no longer be ignored
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Research
DNA suitcases packed with gene therapy cargo
Nano-sized capsules can be unlocked to release drugs on demand
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Podcast
Gabapentin
Louise Crane documents the rise and fall of Gabapentin – from ‘wonder drug’ to illicit substance in just 50 years
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Research
What's your nano poison?
Informatics tool helps researchers visualise complex toxicity datasets
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Research
Sepsis’ sticking point in for a shock
Simple microfluidic method helps detect life-threatening condition earlier
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Business
Lilly to buy Boehringer’s pet vaccines
Deal strengthens Lilly’s animal medicine division following recent acquisition
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Research
Connectosomes smuggle drugs across membranes
Engineered vesicles could cut drug side-effects by delivering them straight into cells using cellular ‘airlocks’
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Opinion
Booster shot
Zika and Ebola have highlighted the pharmaceutical industry’s ability to respond to critical needs
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Feature
Drugging the epigenome
Drugs that change how your genes are switched on or off could change how we treat many diseases, as Rachel Brazil discovers