Medicinal chemistry – Page 45
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ResearchRoadkill: new molecules at the side of the road
Wild animals run down on the roads can open surprising doors for opportunistic biochemists
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FeatureNew opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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FeatureIntracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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ResearchChemoluminescent nanoparticles detect multiple deadly viruses in one go
A detection system can test for multiple viruses in one sample
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ResearchDiamonds to track down origins of diseases of ageing
Fluorescent nanodiamonds reveal the inner workings of neurons
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OpinionHow much does fashion influence chemists?
Is that new reaction the next Nobel-worthy breakthrough, or just a flash in the pan?
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PodcastBromodeoxyuridine
Kat Arney illuminates the story of a molecular ‘highlighter pen’ for growing cells
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OpinionRestarting the mental health pipeline
The lack of UK investment in new drugs for mental health disorders is a problem – but the tide may be about to turn
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CareersThe trials and tribulations of drug discovery
The many pitfalls medicinal chemists face when creating a new drug
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ResearchPoison dart frog toxin made in mirror image
Toxin’s non-natural enantiomer offers new tool to probe nerve disorders
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PodcastBenzoyl peroxide
The blondest blonde, the whitest smile, the clearest complexion – all from one essential compound
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FeaturePersonalised skincare
Nina Notman explores some of the latest scientific approaches skincare companies are using in the quest to develop high-earning anti-ageing cosmetics
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ResearchDibrominated tag helps identify new natural products
New substance allows researchers to find new aldehyde- and ketone-containing natural products
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NewsWHO cancer agency criticised for outdated chemical risk methods
Criticism of carcinogenicity assessments that place processed meat in the same category as mustard gas
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PodcastPARP: Poly (ADP-ribose) polymerase
Kat Arney explains how a protein that repairs broken DNA holds the key to killing cancer cells – but only if you stop it from doing its job
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OpinionRegulatory tightropes
When lobbying and marketing clash with scientific evidence, regulators walk a fine line