Medicinal chemistry – Page 46
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ResearchBlood laser exposes body fluid’s molecular make-up
Optofluidic lasers may inject life into in vivo monitoring of blood components
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NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
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ResearchA drop of drool to analyse asthma
Researchers develop simple asthma diagnosis based on patients’ saliva
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ResearchProbable carcinogens found in e-cigarette vapour
Vaping emits harmful compounds – including propylene glycol and glycerine – as solvents are broken down by heat
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ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
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NewsNo health effects from chemicals from West Virginia spill
January 2014 leak from Freedom Industries’ site at levels too low to harm people’s health
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ResearchKamikaze bacteria travel deep inside tumours to deliver deadly cargo
Engineered bacteria in tandem with chemotherapy show promise in mouse model of cancer
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BusinessJuno CAR-T trial suspended after patient deaths
Immunotherapy study restarted with amended pre-treatment protocol
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NewsUS urged to curb chemicals that harm brain development
NIH-backed coalition calls for immediate action to reduce developmental toxicant exposures
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ResearchTurbocharged synthesis makes antiviral Tamiflu in an hour
Production process showcases how organocatalysis can combine reactions in a single pot
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ResearchGold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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PodcastThiomersal
Kat Arney introduces the organomercury preservative associated with the current controversy around vaccines
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OpinionWe need a global plan to beat resistance
We all need to do our bit and act for the common good if we’re going to protect antibiotics
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NewsHigher lead levels in blood of Flint’s young children
US Centers for Disease Control and Prevention reports levels of lead are of concern
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ResearchMiniature carbon bottles hold promise as nano-reactors
Nanobubbles with hydrophobic interiors also have potential as drug delivery agents
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OpinionLinked data is the future for medicinal chemistry
Paul Groth explains why linked data is starting to revolutionise medicinal chemistry
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ResearchMirror-image trick yields real hits from a virtual chemical library
Scientists use mirror-image protein to identify potential new drugs from a previously unexplored library of natural product enantiomers
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Feature2Heavy drugs gaining momentum
With the first approval of a drug containing deuterium looking imminent, Nina Notman surveys the deuterated drug landscape
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News
New biobank supports Obama’s personalised medicine initiative
Mayo Clinic receives $142 million to shed light on individual differences in health and disease
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NewsWorld faces tough challenge turning words into action on antibiotic resistance
Countries are waking up to the challenge of ‘superbugs’ but agreeing a way forward will be tricky