Medicinal chemistry – Page 47
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ResearchChemical synthesis injects new life into old antibiotics
Approach can construct wide range of new antibiotic candidates from simple chemical building blocks
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News
Large HIV vaccine trial to launch in South Africa
US funding agency will enlist 5400 people for HIV vaccine study in South Africa in November
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NewsInsider trading scandal topples head of Taiwan’s top research body
President of umbrella organisation overseeing 24 research institutions caught up in investigation into offloading of biotech shares prior to poor results
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PodcastTetraethyl lead
For decades, automobile fuel had a dangerous additive: Tetraethyl lead. Matt Gunther explains why a toxic compound was added to our fuel
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PodcastHaloperidol
It failed as a painkiller, but Haldol rapidly became an essential medicine for schizophrenia. Raychelle Burks explains more
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NewsLack of data on BPA exposure in developing countries
Few studies focus on developing countries where regulations around BPA use are less strict
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OpinionWhy we need an allergic reaction
Michael Walker calls for a grand vision to protect people with food allergy
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OpinionCan we wait for e-cigarette trials?
Safety data is needed but is not a reason to ignore vaping now, says Thomas Hartung
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ResearchSmart bandages you press for antibacterial action
Only releasing antibacterials when needed leave bacteria with no time to adapt
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BusinessFDA moves to withdraw swine drug carbadox
Carcinogenic antibiotic has been banned in EU, Canada and Australia for years
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PodcastFluorescein
Kat Arney discovers the compound that first coloured the Chicago river green for St Patrick’s Day
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OpinionDrugs don’t grow on trees
The trope of companies profiteering from academic discoveries doesn’t bear much scrutiny, says Derek Lowe
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BusinessSanofi and Merck & Co end vaccines partnership
Two-decade-long alliance will split by end of 2016
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PodcastOseltamivir
Oseltamivir, or Tamiflu, stockpiling during the 2009 H1N1 epidemic highlighted significant problems with drugs trials policy
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NewsThe huge impact of ‘mini-brains’
‘Mini-brains’ created by Johns Hopkins researchers in the US could revolutionise how drugs and compounds are tested for safety and effectiveness
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NewsUpdated European regulation spells uncertainty for food nanomaterials
Questions over nanomaterial definition could hamper use in foods
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News‘Map’ of chemical landscape could cut animal testing
Searchable database of 10,000 chemicals could help to create safety profiles for untested compounds
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PodcastFlibanserin
Flibanserin was touted to be the female Viagra. Martha Henriques explains why it failed to live up to the hype.
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ResearchPopping nanobubbles let surgeons sound out micro-tumours
Technique that can hunt down and destroy individual cancer cells is set to get clinical trial