Medicinal chemistry – Page 47
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ResearchSynthesis strategy takes the pain out of finding malaria drugs
Compound libraries could help find treatments for a whole host of diseases
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BusinessJoined-up thinking
The rift between contract medicinal chemistry and chemical development needs to be bridged
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OpinionDon’t fear the Crispr
Does simple gene-editing mean the end of traditional medicinal chemistry? Probably not
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BusinessFDA urges labs to test all blood donations for Zika
Agency has also given emergency authorisation to two new Zika blood tests
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BusinessPfizer to buy Astrazeneca’s antibiotics
Deal tops up Pfizer’s late-stage development pipeline, but AZ will retain biological programmes
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OpinionHow to solve global health inequality
Our skills as scientists hold the answer, says the Bill & Melinda Gates Foundation
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OpinionPreparing for the future of pharma
Dave Allen discusses how scenario planning helps to define uncertainty in pharma
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ResearchMagnetic fields deliver cancer-killing bacteria to tumour’s heart
Guided microbes packed with drugs can reach the parts of cancers that other drugs just can’t reach
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ResearchBlood laser exposes body fluid’s molecular make-up
Optofluidic lasers may inject life into in vivo monitoring of blood components
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NewsAntibiotic partnership plans accelerated drug development
Public–private venture will invest $350 million over five years but there are warnings that much more money is still needed
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ResearchA drop of drool to analyse asthma
Researchers develop simple asthma diagnosis based on patients’ saliva
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ResearchProbable carcinogens found in e-cigarette vapour
Vaping emits harmful compounds – including propylene glycol and glycerine – as solvents are broken down by heat
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ResearchNew antibiotic picked from nose bacteria
Discovery suggests human microbiome may be an untapped source of antimicrobial compounds
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NewsNo health effects from chemicals from West Virginia spill
January 2014 leak from Freedom Industries’ site at levels too low to harm people’s health
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ResearchKamikaze bacteria travel deep inside tumours to deliver deadly cargo
Engineered bacteria in tandem with chemotherapy show promise in mouse model of cancer
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BusinessJuno CAR-T trial suspended after patient deaths
Immunotherapy study restarted with amended pre-treatment protocol
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NewsUS urged to curb chemicals that harm brain development
NIH-backed coalition calls for immediate action to reduce developmental toxicant exposures
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ResearchTurbocharged synthesis makes antiviral Tamiflu in an hour
Production process showcases how organocatalysis can combine reactions in a single pot