Medicinal chemistry – Page 49
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PodcastFluorescein
Kat Arney discovers the compound that first coloured the Chicago river green for St Patrick’s Day
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OpinionDrugs don’t grow on trees
The trope of companies profiteering from academic discoveries doesn’t bear much scrutiny, says Derek Lowe
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BusinessSanofi and Merck & Co end vaccines partnership
Two-decade-long alliance will split by end of 2016
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PodcastOseltamivir
Oseltamivir, or Tamiflu, stockpiling during the 2009 H1N1 epidemic highlighted significant problems with drugs trials policy
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NewsThe huge impact of ‘mini-brains’
‘Mini-brains’ created by Johns Hopkins researchers in the US could revolutionise how drugs and compounds are tested for safety and effectiveness
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NewsUpdated European regulation spells uncertainty for food nanomaterials
Questions over nanomaterial definition could hamper use in foods
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News‘Map’ of chemical landscape could cut animal testing
Searchable database of 10,000 chemicals could help to create safety profiles for untested compounds
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PodcastFlibanserin
Flibanserin was touted to be the female Viagra. Martha Henriques explains why it failed to live up to the hype.
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ResearchPopping nanobubbles let surgeons sound out micro-tumours
Technique that can hunt down and destroy individual cancer cells is set to get clinical trial
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ResearchIonic liquids bestow stretch on biomedical sensors
Heart rate and neck movements recognised by soft and stretchable device
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NewsAntibiotic alternatives need to be recruited in fight against resistance
Vaccines, probiotics and other substitutes could help battle antimicrobial resistance as antibiotic effectiveness fades
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NewsDoubts raised about key BPA substitute
Mounting research suggests a favoured bisphenol A replacement has similar biological effects and may be no safer
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FeatureAge of the phage
Hayley Birch discovers how researchers are using proteins from viruses to create new antimicrobial drugs
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ResearchBoost for non-animal toxicology testing
Thousands of compounds have been screened in a bid to develop in vitro toxicity tests
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ResearchAlcoholic liver disease on a chip
Microfluidic simulation provides new platform for drug tests
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OpinionThe kids aren’t alright
Making it more attractive for companies to develop paediatric drugs has the potential to improve everyone’s lives
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BusinessClinical trial death highlights hazards
Pain drug trial has left one dead and five hospitalised in France, with little indication as to the cause of the problems
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