Medicinal chemistry – Page 49
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ResearchCutting edge chemistry in 2015
We take a look back at the year’s most interesting chemical science stories
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Business
Heptares takes on new partners for drug discovery
Firm set to receive over $1bn from research partnerships
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NewsReview calls for tighter controls on antibiotic use in farming
Legally binding targets are needed to tackle resistance worldwide, latest report says
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ResearchA sound idea for treating lung disease
‘Nano-earthquake’ creates a mist of stem cells for potential pulmonary delivery and therapy
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OpinionRethinking risk assessment
Toxicologists must embrace better ways of accounting for low dose effects, argue Annamaria Colacci and Nicole Kleinstreuer
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Business
Drug firms to share chemical compound libraries
AstraZeneca and Sanofi aim to facilitate drug discovery by swapping 210,000 proprietary chemical compounds
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ResearchDetecting leaks in gastrointestinal plumbing
Low-cost capsule can detect bleeding in the stomach in real time
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Research‘Superballs’ can block infection by Ebola virus
Globular glycofullerene molecules prevent virus from evading immune system and entering cells
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NewsPoor management of antibiotics squandering life-saving drugs
Internet and over-the-counter sales along with counterfeit drugs are driving a worldwide rise in antimicrobial resistance
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Research
Early lead exposure linked to sleep problems
Researchers find lead exposure in early childhood is associated with sleep difficulties later on
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BusinessAdvancing animal testing alternatives
Animal rights groups are engaging with researchers and regulators to develop replacement tests and ensure they’re adopted
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FeatureMolecule-making microbes
Extracting terpene drugs from plants is difficult and wasteful, so pharma companies are looking to biosynthesis, as Emiliano Feresin discovers
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BusinessViral cancer therapy approved in the US
T-Vec is the first approved oncolytic virus, but its limited treatment scope means it is unlikely to become a blockbuster
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ResearchEye drops show promise treating cataracts and even reversing damage
Sterol compound can ‘dissolve’ mis-folded proteins to help clear the lens offering hope to 100 million in developing world
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ResearchOral delivery of anticancer drug
Researchers endeavour to limit drug side effects and injections for cancer patients
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ResearchBiomarkers identify stroke victims with cognitive problems
A metabolomics approach to check whether a stroke has affected a patient’s memory or thinking processes
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NewsPoor diagnostics hinder battle against antibiotic resistance
Healthcare workers’ tools to diagnose infections remain stuck in the past
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NewsMalaria vaccine pilot studies recommended by WHO
GlaxoSmithKline’s RTS,S vaccine must undergo further testing before being rolled out, says World Health Organization panel