Medicinal chemistry – Page 50
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ResearchMicroscopic cannon battery to blast disease
Cannon-like tubes shoot tiny bullets when triggered by ultrasound and could deliver drugs
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ResearchDrug labelling problems ironed out by new catalyst
Cost-effective method to tritiate compounds offers way to track drug metabolism while minimising radioactive waste
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ResearchEasy addition of ‘unnatural’ strained rings boon for drug chemists
Technique can slow metabolism of medicines, giving them more time to work
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BusinessFixing the broken antibiotics business model
With rising resistance and doomsday warnings, focus is turning to alternative economic models to boost antibiotic R&D
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ResearchSaliva test detects date rape drug
Detecting GHB and alcohol contaminants in saliva could mean faster treatment for ‘drunk’ A&E patients
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Business
Mexico approves world’s first dengue vaccine
Sanofi’s vaccine protects children and adults against the mosquito-borne disease
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Business
BioAtla and Pfizer to collaborate on antibody research
Two-way agreement to share technology and royalties on new cancer drugs
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ResearchCracking cocaine’s secret to sneaking into the brain
Researchers look to psychoactive substances for tips on drug development
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ResearchCutting edge chemistry in 2015
We take a look back at the year’s most interesting chemical science stories
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Business
Heptares takes on new partners for drug discovery
Firm set to receive over $1bn from research partnerships
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NewsReview calls for tighter controls on antibiotic use in farming
Legally binding targets are needed to tackle resistance worldwide, latest report says
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ResearchA sound idea for treating lung disease
‘Nano-earthquake’ creates a mist of stem cells for potential pulmonary delivery and therapy
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OpinionRethinking risk assessment
Toxicologists must embrace better ways of accounting for low dose effects, argue Annamaria Colacci and Nicole Kleinstreuer
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Business
Drug firms to share chemical compound libraries
AstraZeneca and Sanofi aim to facilitate drug discovery by swapping 210,000 proprietary chemical compounds
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ResearchDetecting leaks in gastrointestinal plumbing
Low-cost capsule can detect bleeding in the stomach in real time
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Research‘Superballs’ can block infection by Ebola virus
Globular glycofullerene molecules prevent virus from evading immune system and entering cells
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NewsPoor management of antibiotics squandering life-saving drugs
Internet and over-the-counter sales along with counterfeit drugs are driving a worldwide rise in antimicrobial resistance