Medicinal chemistry – Page 56
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News
US ramps up rare diseases research
National Institutes of Health spends $29 million to study more than 200 rare diseases
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Business
EMA finalises trial transparency rules
Researcher access reinstated, but company redaction rights may cause issues
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Business
Actavis boosts antibiotics with Durata buyout
$820 million deal gives Actavis control of newly-approved intravenous antibiotic
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Research
BRCA2 protein imaged for first time
Insights into DNA repair mechanism could pave the way for new cancer therapies
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Research
Tea tonic peps up tumour treatment
Green tea polyphenol makes ‘magic bullet’ cancer drug delivery even more powerful
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Podcast
Chemistry World podcast - October 2014
We speak to Jason Sello about the hunt for new antibiotics, and Monique Simmonds explains the chemical role of botanical gardens
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Feature
Transparency measures forced on pharma
Previous misdemeanours are compelling the pharmaceutical industry to be more open with financial information and clinical data, writes Nuala Moran
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Research
Mirror peptides hitch a lift into the cell
Hijacking nature’s tricks to smuggle drugs across the cell membrane
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Research
Nanoparticle studies leave the lab
Scientists take to the outdoors to show that single walled carbon nanotubes accumulate and persist in aquatic sediments
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Feature
Pepping up antibiotics
Industry and academia are turning to antimicrobial peptides to find new antibiotics, Andy Extance discovers
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News
NIH wants scientists to consider sex in research
Preclinical and clinical research is overreliant on male test subjects which can cloud future work in humans
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Business
Review says cheaper drug is safe for eye disease
Cochrane collaboration says side effects of expensive Lucentis and off-label Avastin are similar
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Feature
Faster, cheaper, better diagnostics
Microfluidics researchers are aiming to bring new diagnostic devices into mainstream medicine. Mark Peplow reports
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Feature
Chemistry in bloom
Sarah Houlton discovers the chemistry among the specimens at many botanical gardens
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Research
Painkiller found in plants may not be natural after all
Cow pats from cattle fed tramadol could explain how the drug came to be in an African herb
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Research
Coated nanoparticles show Alzheimer's promise
Gold nanoparticles functionalised with amino acid polymer inhibit the growth of amyloid fibres associated with neurodegenerative disease
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Research
Antimalarial flow synthesis closer to commercialisation
Scientists in Germany hope their continuous flow method will boost accessibility of artemisinin-derived medicines
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Research
Higher levels of some metals in e-cigarette smoke
Scientists call for regulators to help clear smoke and mirrors surrounding vaping safety