Medicinal chemistry – Page 59
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Research
Ionic liquids join battle against antibiotic resistance
Organic salts disrupt biofilms to leave resistant bacteria at the mercy of antibiotics
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ResearchYeast turned into morphine and opioid biofactories
Scientists hope that biotech route could protect the drug supply chain from harvest failures and problems with illicit use
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NewsDoctors turn to experimental Ebola treatments
Drugs and vaccines untested in humans are being trialled on Ebola patients
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ResearchRadiolabels help evaluate emerging cancer treatment
Tracking tools will aid transition of boron neutron capture therapy from bench to hospital
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PodcastMagnesium oxide
You may have created it in a fiery flash or taken it to soothe a burning stomach. Simon Cotton on magnesium oxide
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ResearchKnock-out theory puts new spin on general anaesthesia
Anaesthetics effect on proteins’ electronic structure could explain mystery of how diverse molecules can cause unconsciousness
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Business
Single shot antibiotic approved for skin infections
Third drug in three months approved under US antimicrobials incentive scheme
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ResearchFaulty enzyme link offers new ways to fight Parkinson’s
Research links Parkinson’s disease to an enzyme that affects the functioning of mitochondria
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PodcastChemistry World podcast - August 2014
This month, how artificial comets may explain the origins of asymmetry in life. Plus, we speak to Martyn Poliakoff
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ResearchNanoparticle protects protein drug cargo
Proteins cling to co-polymer thanks to electrostatic interactions
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ResearchBubble wrap could send lab costs packing
Potential bubbles up across wide range of uses as storage and test vessels, especially for poor countries
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ResearchMolecular computer calculates Ebola diagnosis
A prototype device displays a fluorescent ‘E’ in the presence of DNA found in Ebola virus
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PodcastDesomorphine
From potential painkiller to kitchen-cooked heroin replacement, Nate Adams tracks the history of desomorphine
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NewsCall for new models to pay for antibiotics
UK government report on ways to fight resistance follows prime minister’s call for global action
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BusinessEMA wrangles restrain trial data progress
Attempts to balance industry and research interests on transparency draw suggestions of improper collusion
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ResearchOrgan–organ interactions could compound nanoparticle damage
Dual-organ simulation uncovers possible toxicity mechanisms that result in liver injury
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NewsRenewed focus on dementia checked by drug challenges
‘Ticking time bomb’ of global neurodegenerative disease burden will be difficult to defuse
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ResearchSmell of malaria attracts mosquitoes
The malaria parasite changes the odour of infected mice, making them smell tastier to mosquitoes