Medicinal chemistry – Page 60
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Business
Biotech bounced back in 2013, says report
R&D investment increasing, but industry needs to use its cash more wisely
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NewsNickel allergy case highlights nanoparticle unknowns
Chemist’s metal hypersensitivity after weighing powder on open bench underlines safety needs
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ResearchFatal toxins found in ‘edible’ wild mushrooms
Deadly kidney disease linked to one mushroom may also be caused by a related species that was thought to be safe to eat
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Research
Pre-childbirth solvent exposure raises breast cancer risk
Women working with solvents before having children are more at risk
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NewsChina gets tough with polluters
Amendments to country’s 25-year-old environment law paves the way for unlimited fines for environmental damage
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CareersRemote possibilities
Now you can graduate in drug discovery without ever leaving the house, as Sarah Houlton finds out
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Business
Nano risk register not necessary, says BASF
Reach covers the relevant information, and a register risks attracting unwarranted stigma
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ResearchDual warhead kills and disarms bacteria
Compound damages bacterial membrane and disables resistance mechanism in a two-pronged attack
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ResearchThree glowing mice
People’s exposure to nanoparticles could be tested for with skin biopsies
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ResearchElemental discoveries at the cellular level
The concentrations of vital chemical elements in cancer cells has been mapped using a dual technique
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OpinionEngineering serendipity
It takes more than random stumbling to find new reactions, says Derek Lowe
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Business$25bn-plus trade sharpens pharma giants’ focus
Novartis’ asset swaps with GSK and Eli Lilly are the latest steps in an ongoing streamlining process
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FeatureTargeting breast cancer
Tamoxifen has been treating breast cancer for 40 years, but few would have predicted how much this drug would contribute to saving lives, writes John Mann
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OpinionKnown unknowns
New molecules with unpredictable biological activity deserve sensible amounts of respect, says Derek Lowe
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Business
UK to fast-track access to critical medicines
Patients could receive medicines before formal approval in exchange for monitoring data
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BusinessRoche disputes unethical East German trial claims
Internal investigation concludes that 1980s trials were legally run and patients gave proper consent
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