Medicinal chemistry – Page 61
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ReviewIntroduction to biological and small molecule drug research and development
Big molecule pharma
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BusinessJ&J puts trial data in independent hands
Yale University’s YODA seeks to help pharma avoid the dark side by acting as gatekeeper for patient records
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NewsCroatia's vaccines manufacturer left hanging as it enters administration
Lack of government investment puts national immunology institute in crisis
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Business
Novartis in the spotlight in mis-selling investigations
Crackdown on pharma marketing continues with US and Japanese cases
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PodcastConotoxins
Helen Scales finds out how unique toxins found in deadly cone snail stings could herald the next generation of painkillers
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OpinionIs there a drug for that?
Derek Lowe ponders whether anything is truly ‘undruggable’ if we look in the right places
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NewsFlu drug stockpile may be worthless
UK committee asks government to think again on Tamiflu as its effectiveness in a pandemic is in doubt
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OpinionThe morning after the night before
Replacing alcohol with a more benign drug sounds like a great idea, but it faces insurmountable hurdles, says Mark Peplow
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OpinionPut the chemistry back in medicinal chemistry
Pursuing skewed priorities and easy options has impoverished the pharmaceutical industry, says David Lathbury.
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OpinionRolling boulders uphill
Is Derek Lowe troubled by his failure to develop a compound that has made it to the pharmacy shelf?
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Business
Regulator cracks down on 23andMe
Personal genetic profiler ordered to stop selling DNA test kits
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PodcastPotassium bromide
Did chemistry help control tension in the trenches? Brian Clegg investigates potassium bromide
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Business
Novartis sells off blood diagnostics division
$1.7bn deal reinforces firm’s focus on core pharmaceuticals
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News
Rough patch for India’s clinical trial industry
Bad publicity has added to the woes of an industry worried by regulatory uncertainty
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OpinionNatural born chemists
Redesigning nature’s catalysts is tantalising but tricky, says Derek Lowe
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News
Supreme court ruling brings clinical trials to a halt in India
Pressure from campaign group precipitates action that puts 162 drug trials on ice
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BusinessGSK to apply for malaria vaccine approval
Infection protection drops over time, but the firm will go ahead with regulatory submission
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Business
Japan confirms Novartis clinical trial data fabrication
Investigation into blood pressure blockbuster continues
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FeatureSeek and destroy
Nanoparticles that can find specific targets before delivering a drug could change medicine. Akshat Rathi investigates