Medicinal chemistry – Page 61
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OpinionTarget acquired
Knowing a drug’s exact biochemistry has never been a prerequisite for approval, says Derek Lowe, and nor should it be
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Business
Data-sharing partnership for drug discovery
Collaborative project aims to assist medicinal chemistry efforts
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Business
Companies urged to publish hidden clinical trial data
Researchers could acquire data and publish themselves if firms refuse
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News'Scientific censorship' hamstringing psychoactive drug research
New treatments for psychological disorders are being held back by government controls on recreational drugs
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OpinionCompulsory licences: necessity or threat?
Are compulsory licences for patent-protected drugs a necessary measure, or a threat to innovation?
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BusinessClinical trial data release blocked by companies
Abbvie and Intermune sue the European Medicines Agency to stop it making data public
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Business
BASF introduces cell-based allergen test
Non-animal test for cosmetic ingredients to comply with Reach regulation
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FeatureFrom molecules to medicines
Turning an active drug molecule into a finished product requires as much chemistry as developing the drug in the first place, as Phillip Broadwith discovers
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Business
Roche to release Tamiflu trial data
The company will drip feed data to the Cochrane Collaboration, but with some elements redacted
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NewsAntibiotic resistance is a ‘ticking time bomb’
Efforts to tackle the threat will need new thinking, but their may be no easy solutions or short cuts to new drugs
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Opinion
Is lead linked to violence?
Examining the evidence for the link between lead exposure and violence, Paul Illing finds a cautionary tale
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Opinion
New antibiotics: what's the hold up?
It’s more a research problem, than a commercial one, says Derek Lowe
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BusinessUK considers patent rule change for trials
Government to change law that organisations say makes the country less appealing as a location for clinical trials
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NewsPharmaSea to scour ocean depths for new drugs
Bioprospecting project will investigate marine organisms in the search for new antibiotics and central nervous system therapies
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Business
Merck resolves Vytorin case for $688m
Investors say the company knew about Enhance trial failure but withheld information
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CareersToxicologist with pesticides on the brain
Vanessa Fitsanakis’ career in toxicology goes all the way back to the farm where she grew up. Helen Carmichael traces her journey from agriculture to academia
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Business
GSK commits to AllTrials data disclosure
Company will begin publishing all clinical study reports