Medicinal chemistry – Page 63
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Feature
Fast, flexible and flourishing
Paul Workman’s experiences in big pharma, academia and biotech gave him the tools to develop new drugs and spin out successful companies. Sarah Houlton profiles the 2012 Chemistry World entrepreneur of the year
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Feature
The latent threat of tuberculosis
Although TB was close to being eradicated in the developed world, it is a major problem in developing countries. With drug-resistant strains on the increase, Clare Sansom outlines the latest in the fight against this killer disease
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Podcast
Chloral hydrate
Dubbed the 'Mickey Finn', this week's compound has uses in medicine and manipulation
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Business
First HIV drug approved as prevention
Truvada tablets can reduce the risk of infection for an HIV-negative person
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Feature
Drawing on drugs to kick the habit
While pharma companies stand accused of giving up on drugs to help people stop smoking, tobacco firms are looking at controversial nicotine replacement products. Anthony King surveys an area that is problematic on all sides.
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Business
GSK drug shines in HIV trial
HIV–Aids drug candidate dolutegravir outperformed Atripla tablets in Phase III
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Opinion
Silicone safety: the status quo
Public alarm over the use of silicone is unwarranted, says Alan Lansdown
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Business
Good signs for Merck & Co insomnia pill
Suvorexant switches off wakefulness to help patients drop off quicker and stay asleep longer
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Business
More testing needed for ridaforolimus
Marketing approval for anti-cancer drug ridaforolimus has been held up in the US
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Opinion
Peace, love and understanding
Chemists and biologists often view the process of drug discovery very differently
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News
€224 million EU antibiotics initiative launched
The project will bring together the pharmaceutical industry and academia, but some institutes have reservations
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Opinion
21st century toxicology
Thomas Hartung discusses the next generation of toxicity testing and the regulatory science of the future
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Business
HDL drug class struggling after latest flop
The failure of another ‘good’ cholesterol-raising drug and a new genetic study casts shadow over HDL hypothesis
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News
Non-animal testing
L’Oréal has joined the US EPA to help develop alternatives to animal toxicity tests
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News
Voluntary controls on antibiotics on US farms criticised
The US Food and Drug Administration has introduced guidelines to try to cut antibiotic use in livestock
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Feature
Making light work
Could light prove to be the ultimate weapon in the battle against deadly superbugs?